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Genomewide Association Study of Simvastatin Pharmacokinetics

We investigated genetic determinants of single‐dose simvastatin pharmacokinetics in a prospective study of 170 subjects and a retrospective cohort of 59 healthy volunteers. In a microarray‐based genomewide association study with the prospective data, the SLCO1B1 c.521T>C (p.Val174Ala, rs4149056)...

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Detalles Bibliográficos
Autores principales:	Mykkänen, Anssi J. H., Taskinen, Suvi, Neuvonen, Mikko, Paile‐Hyvärinen, Maria, Tarkiainen, E. Katriina, Lilius, Tuomas, Tapaninen, Tuija, Backman, Janne T., Tornio, Aleksi, Niemi, Mikko
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2022
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9540481/ https://www.ncbi.nlm.nih.gov/pubmed/35652242 http://dx.doi.org/10.1002/cpt.2674

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