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Quantitative Proteomics of Hepatic Drug‐Metabolizing Enzymes and Transporters in Patients With Colorectal Cancer Metastasis
The impact of liver cancer metastasis on protein abundance of 22 drug‐metabolizing enzymes (DMEs) and 25 transporters was investigated using liquid chromatography‐tandem accurate mass spectrometry targeted proteomics. Microsomes were prepared from liver tissue taken from 15 healthy individuals and 1...
Autores principales: | Vasilogianni, Areti‐Maria, Al‐Majdoub, Zubida M., Achour, Brahim, Annie Peters, Sheila, Barber, Jill, Rostami‐Hodjegan, Amin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9540503/ https://www.ncbi.nlm.nih.gov/pubmed/35510337 http://dx.doi.org/10.1002/cpt.2633 |
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