Siglec-7 represents a glyco-immune checkpoint for non-exhausted effector memory CD8+ T cells with high functional and metabolic capacities

While inhibitory Siglec receptors are known to regulate myeloid cells, less is known about their expression and function in lymphocytes subsets. Here we identified Siglec-7 as a glyco-immune checkpoint expressed on non-exhausted effector memory CD8+ T cells that exhibit high functional and metabolic...

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Detalles Bibliográficos
Autores principales: Haas, Quentin, Markov, Nikita, Muerner, Lukas, Rubino, Viviana, Benjak, Andrej, Haubitz, Monika, Baerlocher, Gabriela M., Ng, Charlotte K. Y., Münz, Christian, Riether, Carsten, Ochsenbein, Adrian F., Simon, Hans-Uwe, von Gunten, Stephan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9540514/
https://www.ncbi.nlm.nih.gov/pubmed/36211376
http://dx.doi.org/10.3389/fimmu.2022.996746

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