A Plurizyme with Transaminase and Hydrolase Activity Catalyzes Cascade Reactions

Engineering dual‐function single polypeptide catalysts with two abiotic or biotic catalytic entities (or combinations of both) supporting cascade reactions is becoming an important area of enzyme engineering and catalysis. Herein we present the development of a PluriZyme, TR(2)E(2), with efficient n...

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Detalles Bibliográficos
Autores principales: Roda, Sergi, Fernandez‐Lopez, Laura, Benedens, Marius, Bollinger, Alexander, Thies, Stephan, Schumacher, Julia, Coscolín, Cristina, Kazemi, Masoud, Santiago, Gerard, Gertzen, Christoph G. W., Gonzalez‐Alfonso, Jose L., Plou, Francisco J., Jaeger, Karl‐Erich, Smits, Sander H. J., Ferrer, Manuel, Guallar, Víctor
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9540564/
https://www.ncbi.nlm.nih.gov/pubmed/35734849
http://dx.doi.org/10.1002/anie.202207344

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