Novel insights on [1,2]oxazolo[5,4‐e]isoindoles on multidrug resistant acute myeloid leukemia cell line

A series of [1,2]oxazolo[5,4‐e]isoindole derivatives was evaluated against HL‐60 cell line and its multidrug resistance (MDR) variant, HL‐60R, resistant to doxorubicin and to other P‐gp substrates by overexpressing the efflux pump. They displayed antiproliferative activities, with IC(50) values rang...

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Detalles Bibliográficos
Autores principales: Labbozzetta, Manuela, Barreca, Marilia, Spanò, Virginia, Raimondi, Maria Valeria, Poma, Paola, Notarbartolo, Monica, Barraja, Paola, Montalbano, Alessandra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9540667/
https://www.ncbi.nlm.nih.gov/pubmed/35749723
http://dx.doi.org/10.1002/ddr.21962

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9540667/
https://www.ncbi.nlm.nih.gov/pubmed/35749723
http://dx.doi.org/10.1002/ddr.21962

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