Therapeutic effects of adipose-derived mesenchymal stem/stromal cells with enhanced migration ability and hepatocyte growth factor secretion by low-molecular-weight heparin treatment in bleomycin-induced mouse models of systemic sclerosis

BACKGROUND: Adipose-derived mesenchymal stem cells (ASCs) have gained attention as a new treatment for systemic sclerosis (SSc). Low-molecular-weight heparin (LMWH) enhances cell function and stimulates the production of hepatocyte growth factor (HGF) in a variety of cells. This study investigated t...

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Detalles Bibliográficos
Autores principales: Suzuka, Takayasu, Kotani, Takuya, Saito, Takashi, Matsuda, Shogo, Sato, Takako, Takeuchi, Tohru
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9540693/
https://www.ncbi.nlm.nih.gov/pubmed/36207753
http://dx.doi.org/10.1186/s13075-022-02915-6

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