Role of TET dioxygenases in the regulation of both normal and pathological hematopoiesis

The family of ten-eleven translocation dioxygenases (TETs) consists of TET1, TET2, and TET3. Although all TETs are expressed in hematopoietic tissues, only TET2 is commonly found to be mutated in age-related clonal hematopoiesis and hematopoietic malignancies. TET2 mutation causes abnormal epigeneti...

Descripción completa

Detalles Bibliográficos
Autores principales: Joshi, Kanak, Zhang, Lei, Breslin S.J., Peter, Kini, Ameet R., Zhang, Jiwang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9540719/
https://www.ncbi.nlm.nih.gov/pubmed/36203205
http://dx.doi.org/10.1186/s13046-022-02496-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9540719/
https://www.ncbi.nlm.nih.gov/pubmed/36203205
http://dx.doi.org/10.1186/s13046-022-02496-x

Ejemplares similares