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Role of TET dioxygenases in the regulation of both normal and pathological hematopoiesis

The family of ten-eleven translocation dioxygenases (TETs) consists of TET1, TET2, and TET3. Although all TETs are expressed in hematopoietic tissues, only TET2 is commonly found to be mutated in age-related clonal hematopoiesis and hematopoietic malignancies. TET2 mutation causes abnormal epigeneti...

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Detalles Bibliográficos
Autores principales:	Joshi, Kanak, Zhang, Lei, Breslin S.J., Peter, Kini, Ameet R., Zhang, Jiwang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2022
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9540719/ https://www.ncbi.nlm.nih.gov/pubmed/36203205 http://dx.doi.org/10.1186/s13046-022-02496-x

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