Importance of histopathological analysis and molecular genetics in a rare neonatal case of rhabdomyosarcoma

We present a case of a neonate who presented with multiple cutaneous and subcutaneous nodules, which was found to be metastatic embryonal rhabdomyosarcoma. Rhabdomyosarcoma is a soft tissue malignancy that usually occurs in children aged one to five but is rare in neonates. The histopathological ana...

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Autores principales: Gramp, Prudence, Zappala, Tania, Von Schuckmann, Lena, Payton, Diane, Wheller, Laura
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Brief Reports
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9540745/
https://www.ncbi.nlm.nih.gov/pubmed/35500145
http://dx.doi.org/10.1111/ajd.13849
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author Gramp, Prudence
Zappala, Tania
Von Schuckmann, Lena
Payton, Diane
Wheller, Laura
author_facet Gramp, Prudence
Zappala, Tania
Von Schuckmann, Lena
Payton, Diane
Wheller, Laura
author_sort Gramp, Prudence
collection PubMed
description We present a case of a neonate who presented with multiple cutaneous and subcutaneous nodules, which was found to be metastatic embryonal rhabdomyosarcoma. Rhabdomyosarcoma is a soft tissue malignancy that usually occurs in children aged one to five but is rare in neonates. The histopathological analysis and molecular genetics are important in the classification of subtype and in guiding treatment options and informing prognosis.
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spelling pubmed-95407452022-10-14 Importance of histopathological analysis and molecular genetics in a rare neonatal case of rhabdomyosarcoma Gramp, Prudence Zappala, Tania Von Schuckmann, Lena Payton, Diane Wheller, Laura Australas J Dermatol Brief Reports We present a case of a neonate who presented with multiple cutaneous and subcutaneous nodules, which was found to be metastatic embryonal rhabdomyosarcoma. Rhabdomyosarcoma is a soft tissue malignancy that usually occurs in children aged one to five but is rare in neonates. The histopathological analysis and molecular genetics are important in the classification of subtype and in guiding treatment options and informing prognosis. John Wiley and Sons Inc. 2022-05-02 2022-08 /pmc/articles/PMC9540745/ /pubmed/35500145 http://dx.doi.org/10.1111/ajd.13849 Text en © 2022 The Authors. Australasian Journal of Dermatology published by John Wiley & Sons Australia, Ltd on behalf of Australasian College of Dermatologists. https://creativecommons.org/licenses/by/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
spellingShingle Brief Reports
Gramp, Prudence
Zappala, Tania
Von Schuckmann, Lena
Payton, Diane
Wheller, Laura
Importance of histopathological analysis and molecular genetics in a rare neonatal case of rhabdomyosarcoma
title Importance of histopathological analysis and molecular genetics in a rare neonatal case of rhabdomyosarcoma
title_full Importance of histopathological analysis and molecular genetics in a rare neonatal case of rhabdomyosarcoma
title_fullStr Importance of histopathological analysis and molecular genetics in a rare neonatal case of rhabdomyosarcoma
title_full_unstemmed Importance of histopathological analysis and molecular genetics in a rare neonatal case of rhabdomyosarcoma
title_short Importance of histopathological analysis and molecular genetics in a rare neonatal case of rhabdomyosarcoma
title_sort importance of histopathological analysis and molecular genetics in a rare neonatal case of rhabdomyosarcoma
topic Brief Reports
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9540745/
https://www.ncbi.nlm.nih.gov/pubmed/35500145
http://dx.doi.org/10.1111/ajd.13849
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