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The role of the primary motor cortex in motor imagery: A theta burst stimulation study
While mentally simulated actions activate similar neural structures to overt movement, the role of the primary motor cortex (PMC) in motor imagery remains disputed. The aim of the study was to use continuous theta burst stimulation (cTBS) to modulate corticospinal activity to investigate the putativ...
Autores principales: | , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9540768/ https://www.ncbi.nlm.nih.gov/pubmed/35503930 http://dx.doi.org/10.1111/psyp.14077 |
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author | Barhoun, Pamela Fuelscher, Ian Do, Michael He, Jason L. Cerins, Andris Bekkali, Soukayna Youssef, George J. Corp, Daniel Major, Brendan P. Meaney, Dwayne Enticott, Peter G. Hyde, Christian |
author_facet | Barhoun, Pamela Fuelscher, Ian Do, Michael He, Jason L. Cerins, Andris Bekkali, Soukayna Youssef, George J. Corp, Daniel Major, Brendan P. Meaney, Dwayne Enticott, Peter G. Hyde, Christian |
author_sort | Barhoun, Pamela |
collection | PubMed |
description | While mentally simulated actions activate similar neural structures to overt movement, the role of the primary motor cortex (PMC) in motor imagery remains disputed. The aim of the study was to use continuous theta burst stimulation (cTBS) to modulate corticospinal activity to investigate the putative role of the PMC in implicit motor imagery in young adults with typical and atypical motor ability. A randomized, double blind, sham‐controlled, crossover, offline cTBS protocol was applied to 35 young adults. During three separate sessions, adults with typical and low motor ability (developmental coordination disorder [DCD]), received active cTBS to the PMC and supplementary motor area (SMA), and sham stimulation to either the PMC or SMA. Following stimulation, participants completed measures of motor imagery (i.e., hand rotation task) and visual imagery (i.e., letter number rotation task). Although active cTBS significantly reduced corticospinal excitability in adults with typical motor ability, neither task performance was altered following active cTBS to the PMC or SMA, compared to performance after sham cTBS. These results did not differ across motor status (i.e., typical motor ability and DCD). These findings are not consistent with our hypothesis that the PMC (and SMA) is directly involved in motor imagery. Instead, previous motor cortical activation observed during motor imagery may be an epiphenomenon of other neurophysiological processes and/or activity within brain regions involved in motor imagery. This study highlights the need to consider multi‐session theta burst stimulation application and its neural effects when probing the putative role of motor cortices in motor imagery. |
format | Online Article Text |
id | pubmed-9540768 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | John Wiley and Sons Inc. |
record_format | MEDLINE/PubMed |
spelling | pubmed-95407682022-10-14 The role of the primary motor cortex in motor imagery: A theta burst stimulation study Barhoun, Pamela Fuelscher, Ian Do, Michael He, Jason L. Cerins, Andris Bekkali, Soukayna Youssef, George J. Corp, Daniel Major, Brendan P. Meaney, Dwayne Enticott, Peter G. Hyde, Christian Psychophysiology Original Articles While mentally simulated actions activate similar neural structures to overt movement, the role of the primary motor cortex (PMC) in motor imagery remains disputed. The aim of the study was to use continuous theta burst stimulation (cTBS) to modulate corticospinal activity to investigate the putative role of the PMC in implicit motor imagery in young adults with typical and atypical motor ability. A randomized, double blind, sham‐controlled, crossover, offline cTBS protocol was applied to 35 young adults. During three separate sessions, adults with typical and low motor ability (developmental coordination disorder [DCD]), received active cTBS to the PMC and supplementary motor area (SMA), and sham stimulation to either the PMC or SMA. Following stimulation, participants completed measures of motor imagery (i.e., hand rotation task) and visual imagery (i.e., letter number rotation task). Although active cTBS significantly reduced corticospinal excitability in adults with typical motor ability, neither task performance was altered following active cTBS to the PMC or SMA, compared to performance after sham cTBS. These results did not differ across motor status (i.e., typical motor ability and DCD). These findings are not consistent with our hypothesis that the PMC (and SMA) is directly involved in motor imagery. Instead, previous motor cortical activation observed during motor imagery may be an epiphenomenon of other neurophysiological processes and/or activity within brain regions involved in motor imagery. This study highlights the need to consider multi‐session theta burst stimulation application and its neural effects when probing the putative role of motor cortices in motor imagery. John Wiley and Sons Inc. 2022-05-03 2022-10 /pmc/articles/PMC9540768/ /pubmed/35503930 http://dx.doi.org/10.1111/psyp.14077 Text en © 2022 The Authors. Psychophysiology published by Wiley Periodicals LLC on behalf of Society for Psychophysiological Research. https://creativecommons.org/licenses/by/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Original Articles Barhoun, Pamela Fuelscher, Ian Do, Michael He, Jason L. Cerins, Andris Bekkali, Soukayna Youssef, George J. Corp, Daniel Major, Brendan P. Meaney, Dwayne Enticott, Peter G. Hyde, Christian The role of the primary motor cortex in motor imagery: A theta burst stimulation study |
title | The role of the primary motor cortex in motor imagery: A theta burst stimulation study |
title_full | The role of the primary motor cortex in motor imagery: A theta burst stimulation study |
title_fullStr | The role of the primary motor cortex in motor imagery: A theta burst stimulation study |
title_full_unstemmed | The role of the primary motor cortex in motor imagery: A theta burst stimulation study |
title_short | The role of the primary motor cortex in motor imagery: A theta burst stimulation study |
title_sort | role of the primary motor cortex in motor imagery: a theta burst stimulation study |
topic | Original Articles |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9540768/ https://www.ncbi.nlm.nih.gov/pubmed/35503930 http://dx.doi.org/10.1111/psyp.14077 |
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