Coproporphyrin I as an Endogenous Biomarker to Detect Reduced OATP1B Activity and Shift in Elimination Route in Chronic Kidney Disease

Coproporphyrin I (CPI) is an endogenous biomarker of organic anion transporting polypeptide 1B transporter (OATP1B). CPI plasma baseline was reported to increase with severity of chronic kidney disease (CKD). Further, ratio of CPI area under the plasma concentration‐time curve (AUCR) in the presence...

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Detalles Bibliográficos
Autores principales: Takita, Hiroyuki, Scotcher, Daniel, Chu, Xiaoyan, Yee, Ka Lai, Ogungbenro, Kayode, Galetin, Aleksandra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9540787/
https://www.ncbi.nlm.nih.gov/pubmed/35652251
http://dx.doi.org/10.1002/cpt.2672

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9540787/
https://www.ncbi.nlm.nih.gov/pubmed/35652251
http://dx.doi.org/10.1002/cpt.2672

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