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Deletion of Tgfβ signal in activated microglia prolongs hypoxia‐induced retinal neovascularization enhancing Igf1 expression and retinal leukostasis

Retinal neovascularization (NV) is the major cause of severe visual impairment in patients with ischemic eye diseases. While it is known that retinal microglia contribute to both physiological and pathological angiogenesis, the molecular mechanisms by which these glia regulate pathological NV have n...

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Detalles Bibliográficos
Autores principales: Usui‐Ouchi, Ayumi, Eade, Kevin, Giles, Sarah, Ideguchi, Yoichiro, Ouchi, Yasuo, Aguilar, Edith, Wei, Guoqin, Marra, Kyle V., Berlow, Rebecca B., Friedlander, Martin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9540888/
https://www.ncbi.nlm.nih.gov/pubmed/35611927
http://dx.doi.org/10.1002/glia.24218

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