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Deletion of Tgfβ signal in activated microglia prolongs hypoxia‐induced retinal neovascularization enhancing Igf1 expression and retinal leukostasis
Retinal neovascularization (NV) is the major cause of severe visual impairment in patients with ischemic eye diseases. While it is known that retinal microglia contribute to both physiological and pathological angiogenesis, the molecular mechanisms by which these glia regulate pathological NV have n...
Autores principales: | Usui‐Ouchi, Ayumi, Eade, Kevin, Giles, Sarah, Ideguchi, Yoichiro, Ouchi, Yasuo, Aguilar, Edith, Wei, Guoqin, Marra, Kyle V., Berlow, Rebecca B., Friedlander, Martin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley & Sons, Inc.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9540888/ https://www.ncbi.nlm.nih.gov/pubmed/35611927 http://dx.doi.org/10.1002/glia.24218 |
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