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Molecular determinants underlying volume‐regulated anion channel subunit‐dependent oxidation sensitivity

ABSTRACT: The volume‐regulated anion channel (VRAC) is formed by LRRC8 subunits. Besides their role in the maintenance of cell homeostasis, VRACs are critically involved in oxidative stress mechanisms: reactive oxygen species directly modulate VRACs in a subunit‐dependent manner. It was reported tha...

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Detalles Bibliográficos
Autores principales: Bertelli, Sara, Zuccolini, Paolo, Gavazzo, Paola, Pusch, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9540897/
https://www.ncbi.nlm.nih.gov/pubmed/35861288
http://dx.doi.org/10.1113/JP283321