Cargando…

Molecular determinants underlying volume‐regulated anion channel subunit‐dependent oxidation sensitivity

ABSTRACT: The volume‐regulated anion channel (VRAC) is formed by LRRC8 subunits. Besides their role in the maintenance of cell homeostasis, VRACs are critically involved in oxidative stress mechanisms: reactive oxygen species directly modulate VRACs in a subunit‐dependent manner. It was reported tha...

Descripción completa

Detalles Bibliográficos
Autores principales:	Bertelli, Sara, Zuccolini, Paolo, Gavazzo, Paola, Pusch, Michael
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2022
Materias:	Molecular and Cellular
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9540897/ https://www.ncbi.nlm.nih.gov/pubmed/35861288 http://dx.doi.org/10.1113/JP283321

Ejemplares similares

BK Channel in the Physiology and in the Cancer of Pancreatic Duct: Impact and Reliability of BK Openers
por: Zuccolini, Paolo, et al.
Publicado: (2022)

IK Channel-Independent Effects of Clotrimazole and Senicapoc on Cancer Cells Viability and Migration
por: Zuccolini, Paolo, et al.
Publicado: (2023)

NS-11021 Modulates Cancer-Associated Processes Independently of BK Channels in Melanoma and Pancreatic Duct Adenocarcinoma Cell Lines
por: Remigante, Alessia, et al.
Publicado: (2021)

TRPM2 Oxidation Activates Two Distinct Potassium Channels in Melanoma Cells through Intracellular Calcium Increase
por: Ferrera, Loretta, et al.
Publicado: (2021)

Structure-function relationships of the LRRC8 subunits and subdomains of the volume-regulated anion channel (VRAC)
por: Ghouli, Manolia R., et al.
Publicado: (2022)

Human ClCa1 modulates anionic conduction of calcium-dependent chloride currents
por: Hamann, Martine, et al.
Publicado: (2009)

A universally conserved residue in the SUR1 subunit of the K(ATP) channel is essential for translating nucleotide binding at SUR1 into channel opening
por: de Wet, Heidi, et al.
Publicado: (2012)

A structurally derived model of subunit‐dependent NMDA receptor function
por: Gibb, Alasdair J., et al.
Publicado: (2018)

Extracellular Determinants of Anion Discrimination of the Cl(−)/H(+) Antiporter Protein CLC-5
por: De Stefano, Silvia, et al.
Publicado: (2011)

Hypercapnia modulates cAMP signalling and cystic fibrosis transmembrane conductance regulator‐dependent anion and fluid secretion in airway epithelia
por: Turner, Mark J., et al.
Publicado: (2015)

Structure of the human volume regulated anion channel
por: Kefauver, Jennifer M, et al.
Publicado: (2018)

A single point mutation reveals gating of the human ClC-5 Cl(−)/H(+) antiporter
por: De Stefano, Silvia, et al.
Publicado: (2013)

Subunit-specific inhibition of acid sensing ion channels by stomatin-like protein 1
por: Kozlenkov, Alexey, et al.
Publicado: (2014)

Late sodium current blocker GS967 inhibits persistent currents induced by familial hemiplegic migraine type 3 mutations of the SCN1A gene
por: Barbieri, R., et al.
Publicado: (2019)

Role of enteroendocrine L‐cells in arginine vasopressin‐mediated inhibition of colonic anion secretion
por: Pais, Ramona, et al.
Publicado: (2016)

Ion Channel Involvement in Tumor Drug Resistance
por: Altamura, Concetta, et al.
Publicado: (2022)

Kainate receptor pore‐forming and auxiliary subunits regulate channel block by a novel mechanism
por: Brown, Patricia M. G. E., et al.
Publicado: (2016)

Glutamate cycling may drive organic anion transport on the basal membrane of human placental syncytiotrophoblast
por: Lofthouse, Emma M., et al.
Publicado: (2015)

Voltage-Gated Sodium Channel Dysfunctions in Neurological Disorders
por: Barbieri, Raffaella, et al.
Publicado: (2023)

Cellular Physiology and Pathophysiology of EAAT Anion Channels
por: Kovermann, Peter, et al.
Publicado: (2022)

Kv11 (ether‐à‐go‐go‐related gene) voltage‐dependent K(+) channels promote resonance and oscillation of subthreshold membrane potentials
por: Matsuoka, Toshinori, et al.
Publicado: (2020)

Calmodulin and ATP support activity of the Cav1.2 channel through dynamic interactions with the channel
por: Minobe, Etsuko, et al.
Publicado: (2017)

Biphasic voltage‐dependent inactivation of human Na(V)1.3, 1.6 and 1.7 Na(+) channels expressed in rodent insulin‐secreting cells
por: Godazgar, Mahdieh, et al.
Publicado: (2018)

Open-channel blockade is less effective on GluN3B than GluN3A subunit-containing NMDA receptors
por: McClymont, David W., et al.
Publicado: (2012)

Is Neuronal Fatigue the Cause of Migraine?
por: Pusch, Michael, et al.
Publicado: (2022)

KCNQ4 potassium channel subunit deletion leads to exaggerated acoustic startle reflex in mice
por: Maamrah, Baneen, et al.
Publicado: (2023)

The dynamic interplay of PIP(2) and ATP in the regulation of the K(ATP) channel
por: Pipatpolkai, Tanadet, et al.
Publicado: (2022)

Vitamin D is an endogenous partial agonist of the transient receptor potential vanilloid 1 channel
por: Long, Wentong, et al.
Publicado: (2020)

Physiological insight into the conserved properties of Caenorhabditis elegans acid‐sensing degenerin/epithelial sodium channels
por: Kaulich, Eva, et al.
Publicado: (2022)

Phosphorylation regulates the sensitivity of voltage‐gated Kv7.2 channels towards phosphatidylinositol‐4,5‐bisphosphate
por: Salzer, Isabella, et al.
Publicado: (2016)

Intracellular Calcium Mobilization in Response to Ion Channel Regulators via a Calcium-Induced Calcium Release Mechanism
por: Petrou, Terry, et al.
Publicado: (2017)

Control of hypothalamic–pituitary–adrenal stress axis activity by the intermediate conductance calcium-activated potassium channel, SK4
por: Liang, Zhi, et al.
Publicado: (2011)

Functional expression of calcium‐permeable canonical transient receptor potential 4‐containing channels promotes migration of medulloblastoma cells
por: Wei, Wei‐Chun, et al.
Publicado: (2017)

Role of the C‐terminus of SUR in the differential regulation of β‐cell and cardiac K(ATP) channels by MgADP and metabolism
por: Vedovato, Natascia, et al.
Publicado: (2018)

The response of the tandem pore potassium channel TASK-3 (K(2P)9.1) to voltage: gating at the cytoplasmic mouth
por: Ashmole, I, et al.
Publicado: (2009)

Determination of erythrocyte sodium sensitivity in man
por: Oberleithner, Hans, et al.
Publicado: (2013)

Overexpression of leucocyte common antigen (LAR) P-subunit in thyroid carcinomas
por: Konishi, N, et al.
Publicado: (2003)

Obligatory role for PKCδ in PIP(2)‐mediated activation of store‐operated TRPC1 channels in vascular smooth muscle cells
por: Martín‐Aragón Baudel, Miguel A. S., et al.
Publicado: (2020)

Plasmodium falciparum Regulatory Subunit of cAMP-Dependent PKA and Anion Channel Conductance
por: Merckx, Anaïs, et al.
Publicado: (2008)

Kv1.3 is the exclusive voltage-gated K(+) channel of platelets and megakaryocytes: roles in membrane potential, Ca(2+) signalling and platelet count
por: McCloskey, Conor, et al.
Publicado: (2010)

Cannot write session to /tmp/vufind_sessions/sess_fladv3lqalatv7ei9siuah47mm