BMI is positively associated with accelerated epigenetic aging in twin pairs discordant for body mass index

BACKGROUND: Obesity is a heritable complex phenotype that can increase the risk of age‐related outcomes. Biological age can be estimated from DNA methylation (DNAm) using various “epigenetic clocks.” Previous work suggests individuals with elevated weight also display accelerated aging, but results...

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Detalles Bibliográficos
Autores principales: Lundgren, Sara, Kuitunen, Sara, Pietiläinen, Kirsi H., Hurme, Mikko, Kähönen, Mika, Männistö, Satu, Perola, Markus, Lehtimäki, Terho, Raitakari, Olli, Kaprio, Jaakko, Ollikainen, Miina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9540898/
https://www.ncbi.nlm.nih.gov/pubmed/35699258
http://dx.doi.org/10.1111/joim.13528

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9540898/
https://www.ncbi.nlm.nih.gov/pubmed/35699258
http://dx.doi.org/10.1111/joim.13528

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