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Overexpression of estrogen receptor β inhibits cellular functions of human hepatic stellate cells and promotes the anti-fibrosis effect of calycosin via inhibiting STAT3 phosphorylation

BACKGROUND: Estrogen receptor β (ERβ) is the major ER subtype in hepatic stellate cells (HSCs). Previously we reported phytoestrogen calycosin suppressed liver fibrosis progression and inhibited HSC-T6 cell functions, suggesting the effects may be related to ERβ. Here, we explore the effect of overe...

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Detalles Bibliográficos
Autores principales:	Wang, Yaxin, Wu, Canyan, Zhou, Jiahui, Fang, Haiming, Wang, Jiajia
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2022
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9541055/ https://www.ncbi.nlm.nih.gov/pubmed/36207725 http://dx.doi.org/10.1186/s40360-022-00617-y

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