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Accidental Falls in Patients with Hyperkinetic Movement Disorders: A Systematic Review

BACKGROUND: The significance of falls and their repercussions in Parkinson’s disease has been extensively researched. However, despite potentially serious effects on health and quality of life and negative impact on the healthcare system, there is not a sufficient understanding of the role of falls...

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Autores principales: Homann, Carl N., Homann, Barbara, Ivanic, Gerd, Urbanic-Purkart, Tadea
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ubiquity Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9541119/
https://www.ncbi.nlm.nih.gov/pubmed/36303814
http://dx.doi.org/10.5334/tohm.709
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author Homann, Carl N.
Homann, Barbara
Ivanic, Gerd
Urbanic-Purkart, Tadea
author_facet Homann, Carl N.
Homann, Barbara
Ivanic, Gerd
Urbanic-Purkart, Tadea
author_sort Homann, Carl N.
collection PubMed
description BACKGROUND: The significance of falls and their repercussions in Parkinson’s disease has been extensively researched. However, despite potentially serious effects on health and quality of life and negative impact on the healthcare system, there is not a sufficient understanding of the role of falls in hyperkinetic movement disorders (HKMDs). This review aims to provide an overview of the prevalence of falls, injuries, and preventive measures in the most common HKMDs. METHODS: Studies up to May 1, 2022 were searched in PubMed using Medical Subjects Headings of relatively prevalent HKMDs associated with the terms “accidental falls”, “injuries”, “fractures”, and “accident prevention”. RESULTS: In our review of 37 studies out of 155, we found evidence that for several HKMDs, such as spinocerebellar ataxia, essential tremor, Huntington’s disease, and dystonia, fall risk is increased. Falls were reported in up to 84% of spinocerebellar ataxia patients, 59% of essential tremor patients, and 79% of Huntington’s patients, with 65% of the latter falling frequently. Injuries occurred in up to 73% in Huntington and 74% in ataxia patients. Most of the common diseases characterized by HKMDs were investigated for both fall causes and consequences, but prevention studies were limited to spinocerebellar ataxia and Huntington’s disease. DISCUSSION: The limited available data suggest that patients with several HKMDs can be considered to be at increased risk of falling and that the consequences can be serious. As a result, physicians should be advised to include fall exploration in their routine workup and provide advice for safer mobility. In general, more research into fall-related concerns in HKMDs is necessary. HIGHLIGHTS: In contrast to Parkinson’s disease, the prevalence of accidental falls, their repercussions, and preventive strategies are under-investigated in hyperkinetic movement disorders (HKMDs). Several HKMDs such as essential tremor, ataxia, and Huntington’s disease have reported fall rates of up to 84% and fall-related injury rates of up to 74%. Therefore, routine examinations of HKMD patients should include a fall exploration and provide advice on safe mobility.
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spelling pubmed-95411192022-10-26 Accidental Falls in Patients with Hyperkinetic Movement Disorders: A Systematic Review Homann, Carl N. Homann, Barbara Ivanic, Gerd Urbanic-Purkart, Tadea Tremor Other Hyperkinet Mov (N Y) Review BACKGROUND: The significance of falls and their repercussions in Parkinson’s disease has been extensively researched. However, despite potentially serious effects on health and quality of life and negative impact on the healthcare system, there is not a sufficient understanding of the role of falls in hyperkinetic movement disorders (HKMDs). This review aims to provide an overview of the prevalence of falls, injuries, and preventive measures in the most common HKMDs. METHODS: Studies up to May 1, 2022 were searched in PubMed using Medical Subjects Headings of relatively prevalent HKMDs associated with the terms “accidental falls”, “injuries”, “fractures”, and “accident prevention”. RESULTS: In our review of 37 studies out of 155, we found evidence that for several HKMDs, such as spinocerebellar ataxia, essential tremor, Huntington’s disease, and dystonia, fall risk is increased. Falls were reported in up to 84% of spinocerebellar ataxia patients, 59% of essential tremor patients, and 79% of Huntington’s patients, with 65% of the latter falling frequently. Injuries occurred in up to 73% in Huntington and 74% in ataxia patients. Most of the common diseases characterized by HKMDs were investigated for both fall causes and consequences, but prevention studies were limited to spinocerebellar ataxia and Huntington’s disease. DISCUSSION: The limited available data suggest that patients with several HKMDs can be considered to be at increased risk of falling and that the consequences can be serious. As a result, physicians should be advised to include fall exploration in their routine workup and provide advice for safer mobility. In general, more research into fall-related concerns in HKMDs is necessary. HIGHLIGHTS: In contrast to Parkinson’s disease, the prevalence of accidental falls, their repercussions, and preventive strategies are under-investigated in hyperkinetic movement disorders (HKMDs). Several HKMDs such as essential tremor, ataxia, and Huntington’s disease have reported fall rates of up to 84% and fall-related injury rates of up to 74%. Therefore, routine examinations of HKMD patients should include a fall exploration and provide advice on safe mobility. Ubiquity Press 2022-10-07 /pmc/articles/PMC9541119/ /pubmed/36303814 http://dx.doi.org/10.5334/tohm.709 Text en Copyright: © 2022 The Author(s) https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution 4.0 International License (CC-BY 4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. See http://creativecommons.org/licenses/by/4.0/.
spellingShingle Review
Homann, Carl N.
Homann, Barbara
Ivanic, Gerd
Urbanic-Purkart, Tadea
Accidental Falls in Patients with Hyperkinetic Movement Disorders: A Systematic Review
title Accidental Falls in Patients with Hyperkinetic Movement Disorders: A Systematic Review
title_full Accidental Falls in Patients with Hyperkinetic Movement Disorders: A Systematic Review
title_fullStr Accidental Falls in Patients with Hyperkinetic Movement Disorders: A Systematic Review
title_full_unstemmed Accidental Falls in Patients with Hyperkinetic Movement Disorders: A Systematic Review
title_short Accidental Falls in Patients with Hyperkinetic Movement Disorders: A Systematic Review
title_sort accidental falls in patients with hyperkinetic movement disorders: a systematic review
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9541119/
https://www.ncbi.nlm.nih.gov/pubmed/36303814
http://dx.doi.org/10.5334/tohm.709
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