Successful treatment of a child's pityriasis rubra pilaris (PRP) with ustekinumab and acitretin

Pityriasis rubra pilaris (PRP) is a rare inflammatory skin disease that occurs with phenotypic variability in adults of all ages as well as in children. Data on the treatment of PRP is limited. Here, we report a 5‐year‐old girl with widespread skin involvement and prominent palmoplantar hyperkeratos...

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Autores principales: Katharina, Medek, Sylvia, Selhofer, Matthias, Buchner, Ulrich, Mrowietz, Martin, Laimer
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2022
Materias:
Brief Reports
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9541132/
https://www.ncbi.nlm.nih.gov/pubmed/35859269
http://dx.doi.org/10.1111/pde.14994
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author Katharina, Medek
Sylvia, Selhofer
Matthias, Buchner
Ulrich, Mrowietz
Martin, Laimer
author_facet Katharina, Medek
Sylvia, Selhofer
Matthias, Buchner
Ulrich, Mrowietz
Martin, Laimer
author_sort Katharina, Medek
collection PubMed
description Pityriasis rubra pilaris (PRP) is a rare inflammatory skin disease that occurs with phenotypic variability in adults of all ages as well as in children. Data on the treatment of PRP is limited. Here, we report a 5‐year‐old girl with widespread skin involvement and prominent palmoplantar hyperkeratosis who was initially treated for psoriasis. After reevaluation, a diagnosis of PRP was made, and the patient had an excellent therapeutic response to ustekinumab and acitretin.
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spelling pubmed-95411322022-10-14 Successful treatment of a child's pityriasis rubra pilaris (PRP) with ustekinumab and acitretin Katharina, Medek Sylvia, Selhofer Matthias, Buchner Ulrich, Mrowietz Martin, Laimer Pediatr Dermatol Brief Reports Pityriasis rubra pilaris (PRP) is a rare inflammatory skin disease that occurs with phenotypic variability in adults of all ages as well as in children. Data on the treatment of PRP is limited. Here, we report a 5‐year‐old girl with widespread skin involvement and prominent palmoplantar hyperkeratosis who was initially treated for psoriasis. After reevaluation, a diagnosis of PRP was made, and the patient had an excellent therapeutic response to ustekinumab and acitretin. Blackwell Publishing Ltd 2022-07-20 2022 /pmc/articles/PMC9541132/ /pubmed/35859269 http://dx.doi.org/10.1111/pde.14994 Text en © 2022 The Authors. Pediatric Dermatology published by Wiley Periodicals LLC. https://creativecommons.org/licenses/by-nc/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc/4.0/ (https://creativecommons.org/licenses/by-nc/4.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited and is not used for commercial purposes.
spellingShingle Brief Reports
Katharina, Medek
Sylvia, Selhofer
Matthias, Buchner
Ulrich, Mrowietz
Martin, Laimer
Successful treatment of a child's pityriasis rubra pilaris (PRP) with ustekinumab and acitretin
title Successful treatment of a child's pityriasis rubra pilaris (PRP) with ustekinumab and acitretin
title_full Successful treatment of a child's pityriasis rubra pilaris (PRP) with ustekinumab and acitretin
title_fullStr Successful treatment of a child's pityriasis rubra pilaris (PRP) with ustekinumab and acitretin
title_full_unstemmed Successful treatment of a child's pityriasis rubra pilaris (PRP) with ustekinumab and acitretin
title_short Successful treatment of a child's pityriasis rubra pilaris (PRP) with ustekinumab and acitretin
title_sort successful treatment of a child's pityriasis rubra pilaris (prp) with ustekinumab and acitretin
topic Brief Reports
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9541132/
https://www.ncbi.nlm.nih.gov/pubmed/35859269
http://dx.doi.org/10.1111/pde.14994
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