Drug‐dependent inhibition of nucleotide hydrolysis in the heterodimeric ABC multidrug transporter PatAB from Streptococcus pneumoniae

The bacterial heterodimeric ATP‐binding cassette (ABC) multidrug exporter PatAB has a critical role in conferring antibiotic resistance in multidrug‐resistant infections by Streptococcus pneumoniae. As with other heterodimeric ABC exporters, PatAB contains two transmembrane domains that form a drug...

Descripción completa

Detalles Bibliográficos
Autores principales: Guffick, Charlotte, Hsieh, Pei‐Yu, Ali, Anam, Shi, Wilma, Howard, Julie, Chinthapalli, Dinesh K., Kong, Alex C., Salaa, Ihsene, Crouch, Lucy I., Ansbro, Megan R., Isaacson, Shoshanna C., Singh, Himansha, Barrera, Nelson P., Nair, Asha V., Robinson, Carol V., Deery, Michael J., van Veen, Hendrik W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9541285/
https://www.ncbi.nlm.nih.gov/pubmed/35066976
http://dx.doi.org/10.1111/febs.16366

Ejemplares similares

Ejemplares similares