Short‐ and long‐term effects of body weight, calorie restriction and gastric bypass on CYP1A2, CYP2C19 and CYP2C9 activity

AIM: Roux‐en‐Y gastric bypass (RYGB) may influence drug disposition due to surgery‐induced gastrointestinal alterations and/or subsequent weight loss. The objective was to compare short‐ and long‐term effects of RYGB and diet on the metabolic ratios of paraxanthine/caffeine (cytochrome P450 [CYP] 1A...

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Detalles Bibliográficos
Autores principales: Kvitne, Kine Eide, Krogstad, Veronica, Wegler, Christine, Johnson, Line Kristin, Kringen, Marianne K., Hovd, Markus Herberg, Hertel, Jens K., Heijer, Maria, Sandbu, Rune, Skovlund, Eva, Artursson, Per, Karlsson, Cecilia, Andersson, Shalini, Andersson, Tommy B., Hjelmesæth, Jøran, Åsberg, Anders, Jansson‐Löfmark, Rasmus, Christensen, Hege, Robertsen, Ida
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9541356/
https://www.ncbi.nlm.nih.gov/pubmed/35404513
http://dx.doi.org/10.1111/bcp.15349

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