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Human cDC1s display constitutive activation of the UPR sensor IRE1

The intracellular mechanisms safeguarding DC function are of biomedical interest in several immune‐related diseases. Type 1 conventional DCs (cDC1s) are prominent targets of immunotherapy typified by constitutive activation of the unfolded protein response (UPR) sensor IRE1. Through its RNase domain...

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Detalles Bibliográficos
Autores principales:	García‐González, Paulina, Fernández, Dominique, Gutiérrez, Diane, Parra‐Cordero, Mauro, Osorio, Fabiola
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2022
Materias:	Adaptive immunity
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9541385/ https://www.ncbi.nlm.nih.gov/pubmed/35419836 http://dx.doi.org/10.1002/eji.202149774

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