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Functionalisation of vitamin B(12) derivatives with a cobalt β-phenyl ligand boosters antimetabolite activity in bacteria
This study describes the syntheses of four singly- and two doubly-modified vitamin B(12) derivatives for generating antimetabolites of Lactobacillus delbrueckii (L. delbrueckii). The two most potent antagonists, a Co(β)-phenyl-cobalamin-c,8-lactam and a 10-bromo-Co(β)-phenylcobalamin combine a c-lac...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
The Royal Society of Chemistry
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9541496/ https://www.ncbi.nlm.nih.gov/pubmed/36320527 http://dx.doi.org/10.1039/d2ra05748d |