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Delayed concentration effect models for dabigatran anticoagulation

INTRODUCTION: Dabigatran is an anticoagulant with potential use during cardiopulmonary bypass in children and adults. The pharmacokinetic–pharmacodynamic relationship for dabigatran anticoagulation effect was investigated in an intact animal model using rabbits. METHODS: Ten male New Zealand white r...

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Detalles Bibliográficos
Autores principales: Eaton, Michael P., Nadtochiy, Sergiy M., Stefanos, Tatsiana, LeMoine, Dana, Anderson, Brian J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9541555/
https://www.ncbi.nlm.nih.gov/pubmed/35735989
http://dx.doi.org/10.1111/pan.14511