Cargando…

Future opportunities for research in rescue treatments

Clinical studies of rescue medications for seizure clusters are limited and are designed to satisfy regulatory requirements, which may not fully consider the needs of the diverse patient population that experiences seizure clusters or utilize rescue medication. The purpose of this narrative review i...

Descripción completa

Detalles Bibliográficos
Autores principales:	Wheless, James W., Friedman, Daniel, Krauss, Gregory L., Rao, Vikram R., Sperling, Michael R., Carrazana, Enrique, Rabinowicz, Adrian L.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2022
Materias:	Special Issue Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9541657/ https://www.ncbi.nlm.nih.gov/pubmed/35822912 http://dx.doi.org/10.1111/epi.17363

Ejemplares similares

Treatment of Seizure Clusters in Epilepsy: A Narrative Review on Rescue Therapies
por: Becker, Danielle A., et al.
Publicado: (2023)

Significant improvements in SEIzure interVAL (time between seizure clusters) across time in patients treated with diazepam nasal spray as intermittent rescue therapy for seizure clusters
por: Misra, Sunita N., et al.
Publicado: (2022)

Overcoming the challenges of developing an intranasal diazepam rescue therapy for the treatment of seizure clusters
por: Cloyd, James, et al.
Publicado: (2021)

Use of second doses of Valtoco® (diazepam nasal spray) across 24 hours after the initial dose for out‐of‐hospital seizure clusters: Results from a phase 3, open‐label, repeat‐dose safety study
por: Sperling, Michael R., et al.
Publicado: (2022)

Implications of Seizure-Cluster Treatment on Healthcare Utilization: Use of Approved Rescue Medications
por: Rabinowicz, Adrian L, et al.
Publicado: (2022)

Safety of Diazepam Nasal Spray in Pediatric Patients With Developmental Epileptic Encephalopathies: Results From a Long-term Phase 3 Safety Study
por: Tarquinio, Daniel, et al.
Publicado: (2023)

Lack of clinically relevant differences in safety and pharmacokinetics after second‐dose administration of intranasal diazepam within 4 h for acute treatment of seizure clusters: A population analysis
por: Cascino, Gregory D., et al.
Publicado: (2022)

Use of intranasal rescue therapy for seizure clusters in students with epilepsy: Nurses’ knowledge, perceptions, and practice
por: Santilli, Nancy, et al.
Publicado: (2023)

Future Developments in Geographical Agent‐Based Models: Challenges and Opportunities
por: Heppenstall, Alison, et al.
Publicado: (2020)

Clarification of Dalfampridine Labeled Indications
por: Rabinowicz, Adrian L., et al.
Publicado: (2012)

The nose has it: Opportunities and challenges for intranasal drug administration for neurologic conditions including seizure clusters
por: Chung, Steve, et al.
Publicado: (2022)

Improvement of Intranasal Drug Delivery with Intravail(®) Alkylsaccharide Excipient as a Mucosal Absorption Enhancer Aiding in the Treatment of Conditions of the Central Nervous System
por: Rabinowicz, Adrian L., et al.
Publicado: (2021)

Optimizing Absorption for Intranasal Delivery of Drugs Targeting the Central Nervous System Using Alkylsaccharide Permeation Enhancers
por: Madden, Stuart, et al.
Publicado: (2023)

Final results from a Phase 3, long‐term, open‐label, repeat‐dose safety study of diazepam nasal spray for seizure clusters in patients with epilepsy
por: Wheless, James W., et al.
Publicado: (2021)

Consistent safety and tolerability of Valtoco(®) (diazepam nasal spray) in relationship to usage frequency in patients with seizure clusters: Interim results from a phase 3, long‐term, open‐label, repeat‐dose safety study
por: Miller, Ian, et al.
Publicado: (2021)

Evaluation of diazepam nasal spray in patients with epilepsy concomitantly using maintenance benzodiazepines: An interim subgroup analysis from a phase 3, long‐term, open‐label safety study
por: Segal, Eric B., et al.
Publicado: (2021)

Pharmacokinetics and safety of VALTOCO (NRL‐1; diazepam nasal spray) in patients with epilepsy during seizure (ictal/peri‐ictal) and nonseizure (interictal) conditions: A phase 1, open‐label study
por: Hogan, Robert Edward, et al.
Publicado: (2020)

Developing Peri-Operative Rehabilitation in Degenerative Cervical Myelopathy [AO Spine RECODE-DCM Research Priority Number 6]: An Unexplored Opportunity?
por: Boerger, Timothy F., et al.
Publicado: (2022)

Developing Novel Therapies for Degenerative Cervical Myelopathy [AO Spine RECODE-DCM Research Priority Number 7]: Opportunities From Restorative Neurobiology
por: Gharooni, Aref-Ali, et al.
Publicado: (2022)

Tumor Cell Dormancy and Reactivation in Bone: Skeletal Biology and Therapeutic Opportunities
por: Byrne, Niall M, et al.
Publicado: (2019)

Delivery of healthcare and healthcare education in the digital era and beyond: opportunities and considerations
por: Chung, Seon Yoon
Publicado: (2023)

Psychiatric neuroimaging research in Brazil: historical overview, current challenges, and future opportunities
por: Busatto, Geraldo, et al.
Publicado: (2020)

The use of PROMs and shared decision‐making in medical encounters with patients: An opportunity to deliver value‐based health care to patients
por: Damman, Olga C., et al.
Publicado: (2019)

Manganese in PET imaging: Opportunities and challenges
por: Brandt, Marie, et al.
Publicado: (2019)

Neglected tropical disease control in a world with COVID-19: an opportunity and a necessity for innovation
por: Brooker, Simon J, et al.
Publicado: (2020)

Rescue therapies for seizure clusters: Pharmacology and target of treatments
por: Gidal, Barry, et al.
Publicado: (2022)

Global bioethics: it’s past and future
por: Macpherson, Cheryl
Publicado: (2022)

Podoconiosis: key priorities for research and implementation
por: Deribe, Kebede, et al.
Publicado: (2020)

Perinatal Depression: Challenges and Opportunities
por: Dagher, Rada K., et al.
Publicado: (2021)

CLIPs to the rescue
por: Dove, Alan W.
Publicado: (2002)

Challenges for future directions for artificial intelligence integrated nursing simulation education
por: Jung, Sunyoung
Publicado: (2023)

Microbial biotechnology for the synthesis of (pro)vitamins, biopigments and antioxidants: challenges and opportunities
por: Revuelta, Jose L., et al.
Publicado: (2016)

Bacterial minicells to the rescue: cyto‐Immunotherapy for the treatment of late stage cancers with minimal to no toxicity
por: Brahmbhatt, Himanshu, et al.
Publicado: (2021)

Evaluation of Pharmacokinetics and Dose Proportionality of Diazepam After Intranasal Administration of NRL‐1 to Healthy Volunteers
por: Tanimoto, Sarina, et al.
Publicado: (2020)

Investigating flavour characteristics of British ale yeasts: techniques, resources and opportunities for innovation
por: Parker, Neva, et al.
Publicado: (2015)

Food and waterborne parasites in Africa - threats and opportunities
por: Robertson, Lucy J., et al.
Publicado: (2020)

Ethics and Responsibility of Scientific Researchers in a Pandemic Era
por: Lee, Kyung-Hee
Publicado: (2021)

Oral antiviral treatments for COVID-19: opportunities and challenges
por: Rahmah, Laila, et al.
Publicado: (2022)

Measuring institutional and structural racism in research on adolescence and developmental science
por: Neblett, Enrique W., et al.
Publicado: (2022)

Environmental Health Research Involving Human Subjects: Ethical Issues
por: Resnik, David B.
Publicado: (2008)

Cannot write session to /tmp/vufind_sessions/sess_vbmrdrjek0gdp26sh70qtmclij