Development of organ‐specific autoimmunity by dysregulated Aire expression

Deficiency for AIRE/Aire in both humans and mice results in the development of organ‐specific autoimmune disease. We tested whether augmented and/or dysregulated AIRE/Aire expression might be also prone to the breakdown of self‐tolerance. To define the effect of augmented Aire expression on the deve...

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Detalles Bibliográficos
Autores principales: Nishijima, Hitoshi, Sugita, Mizuki, Umezawa, Natsuka, Kimura, Naoki, Sasaki, Hirokazu, Kawano, Hiroshi, Nishioka, Yasuhiko, Matsumoto, Minoru, Oya, Takeshi, Tsuneyama, Koichi, Morimoto, Junko, Matsumoto, Mitsuru
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Short Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9541787/
https://www.ncbi.nlm.nih.gov/pubmed/35313042
http://dx.doi.org/10.1111/imcb.12546

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