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Changes in volumetric bone mineral density and bone quality after Roux‐en‐Y gastric bypass: A meta‐analysis with meta‐regression
This meta‐analysis aimed to assess the effect of Roux‐en‐Y gastric bypass (RYGB) on three‐dimensionally assessed volumetric bone mineral density (vBMD) with the effect of time on these changes, on bone quality, and the agreement of dual‐energy X‐ray absorptiometry (DXA) with quantitative computed to...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9541815/ https://www.ncbi.nlm.nih.gov/pubmed/35665991 http://dx.doi.org/10.1111/obr.13479 |
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author | Hernández‐Martínez, Alba Veras, Lucas Boppre, Giorjines Soriano‐Maldonado, Alberto Oliveira, José Diniz‐Sousa, Florêncio Fonseca, Hélder |
author_facet | Hernández‐Martínez, Alba Veras, Lucas Boppre, Giorjines Soriano‐Maldonado, Alberto Oliveira, José Diniz‐Sousa, Florêncio Fonseca, Hélder |
author_sort | Hernández‐Martínez, Alba |
collection | PubMed |
description | This meta‐analysis aimed to assess the effect of Roux‐en‐Y gastric bypass (RYGB) on three‐dimensionally assessed volumetric bone mineral density (vBMD) with the effect of time on these changes, on bone quality, and the agreement of dual‐energy X‐ray absorptiometry (DXA) with quantitative computed tomography (QCT) or high‐resolution peripheral QCT (HR‐pQCT) estimates of bone loss. We searched PubMed, Web of Science, Cochrane, Scopus, and EBSCO. Longitudinal studies on adults undergoing RYGB in which vBMD was assessed by QCT or HR‐pQCT with ≥6 months follow‐up were included. Total hip (TH) changes were reported in four studies, lumbar spine (LS) in eight, radius in eight, and tibia in seven. Significant post‐RYGB vBMD reductions occurred at all skeletal sites analyzed. Meta‐regression revealed that time post‐RYGB was significantly associated with vBMD deterioration in all skeletal sites except at the TH. RYGB also led to significant deterioration on bone quality. DXA underestimated LS and overestimated TH bone losses post‐RYGB. In conclusion, RYGB was associated with significant vBMD loss, which makes screening of bone mass progression by three‐dimensional technology a crucial clinical issue to prevent fracture risk and osteoporosis. |
format | Online Article Text |
id | pubmed-9541815 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | John Wiley and Sons Inc. |
record_format | MEDLINE/PubMed |
spelling | pubmed-95418152022-10-14 Changes in volumetric bone mineral density and bone quality after Roux‐en‐Y gastric bypass: A meta‐analysis with meta‐regression Hernández‐Martínez, Alba Veras, Lucas Boppre, Giorjines Soriano‐Maldonado, Alberto Oliveira, José Diniz‐Sousa, Florêncio Fonseca, Hélder Obes Rev Bariatric Surgery/Body Composition This meta‐analysis aimed to assess the effect of Roux‐en‐Y gastric bypass (RYGB) on three‐dimensionally assessed volumetric bone mineral density (vBMD) with the effect of time on these changes, on bone quality, and the agreement of dual‐energy X‐ray absorptiometry (DXA) with quantitative computed tomography (QCT) or high‐resolution peripheral QCT (HR‐pQCT) estimates of bone loss. We searched PubMed, Web of Science, Cochrane, Scopus, and EBSCO. Longitudinal studies on adults undergoing RYGB in which vBMD was assessed by QCT or HR‐pQCT with ≥6 months follow‐up were included. Total hip (TH) changes were reported in four studies, lumbar spine (LS) in eight, radius in eight, and tibia in seven. Significant post‐RYGB vBMD reductions occurred at all skeletal sites analyzed. Meta‐regression revealed that time post‐RYGB was significantly associated with vBMD deterioration in all skeletal sites except at the TH. RYGB also led to significant deterioration on bone quality. DXA underestimated LS and overestimated TH bone losses post‐RYGB. In conclusion, RYGB was associated with significant vBMD loss, which makes screening of bone mass progression by three‐dimensional technology a crucial clinical issue to prevent fracture risk and osteoporosis. John Wiley and Sons Inc. 2022-06-03 2022-08 /pmc/articles/PMC9541815/ /pubmed/35665991 http://dx.doi.org/10.1111/obr.13479 Text en © 2022 The Authors. Obesity Reviews published by John Wiley & Sons Ltd on behalf of World Obesity Federation. https://creativecommons.org/licenses/by-nc/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc/4.0/ (https://creativecommons.org/licenses/by-nc/4.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited and is not used for commercial purposes. |
spellingShingle | Bariatric Surgery/Body Composition Hernández‐Martínez, Alba Veras, Lucas Boppre, Giorjines Soriano‐Maldonado, Alberto Oliveira, José Diniz‐Sousa, Florêncio Fonseca, Hélder Changes in volumetric bone mineral density and bone quality after Roux‐en‐Y gastric bypass: A meta‐analysis with meta‐regression |
title | Changes in volumetric bone mineral density and bone quality after Roux‐en‐Y gastric bypass: A meta‐analysis with meta‐regression |
title_full | Changes in volumetric bone mineral density and bone quality after Roux‐en‐Y gastric bypass: A meta‐analysis with meta‐regression |
title_fullStr | Changes in volumetric bone mineral density and bone quality after Roux‐en‐Y gastric bypass: A meta‐analysis with meta‐regression |
title_full_unstemmed | Changes in volumetric bone mineral density and bone quality after Roux‐en‐Y gastric bypass: A meta‐analysis with meta‐regression |
title_short | Changes in volumetric bone mineral density and bone quality after Roux‐en‐Y gastric bypass: A meta‐analysis with meta‐regression |
title_sort | changes in volumetric bone mineral density and bone quality after roux‐en‐y gastric bypass: a meta‐analysis with meta‐regression |
topic | Bariatric Surgery/Body Composition |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9541815/ https://www.ncbi.nlm.nih.gov/pubmed/35665991 http://dx.doi.org/10.1111/obr.13479 |
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