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Evaluation of subclasses for T4‐classified squamous cell carcinoma of the external auditory canal
BACKGROUND: T4‐classified squamous cell carcinoma (SCC) of external auditory canal (EAC) can potentially involve different anatomical structures, which could translate into different treatment strategies and survival outcomes within one classification. Our aim is to evaluate the clinical added value...
| Autores principales: | , , , , , , , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
John Wiley & Sons, Inc.
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9541903/ https://www.ncbi.nlm.nih.gov/pubmed/35560966 http://dx.doi.org/10.1002/hed.27082 |
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| author | Nabuurs, Cindy H. Kievit, Wietske Leemans, C. René Smit, Conrad F. G. M. van den Brekel, Michiel W. M. Pauw, Robert J. van der Laan, Bernard F. A. M. Jansen, Jeroen C. Lacko, Martin Braunius, Weibel W. Dai, Chunfu Shi, Xunbei Danesi, Giovanni Bouček, Jan Takes, Robert P. Kunst, Henricus P. M. |
| author_facet | Nabuurs, Cindy H. Kievit, Wietske Leemans, C. René Smit, Conrad F. G. M. van den Brekel, Michiel W. M. Pauw, Robert J. van der Laan, Bernard F. A. M. Jansen, Jeroen C. Lacko, Martin Braunius, Weibel W. Dai, Chunfu Shi, Xunbei Danesi, Giovanni Bouček, Jan Takes, Robert P. Kunst, Henricus P. M. |
| author_sort | Nabuurs, Cindy H. |
| collection | PubMed |
| description | BACKGROUND: T4‐classified squamous cell carcinoma (SCC) of external auditory canal (EAC) can potentially involve different anatomical structures, which could translate into different treatment strategies and survival outcomes within one classification. Our aim is to evaluate the clinical added value of T4‐subclasses proposed by Lavieille and by Zanoletti. METHODS: Retrospective data, including patients with primary operated cT4‐classified EAC SCC, was obtained from 12 international hospitals. We subclassified according to the T4‐subclasses. The treatment strategies, disease‐free survival (DFS) and overall survival per subclass were calculated. RESULTS: A total of 130 T4‐classified EAC SCC were included. We found commonly used treatment strategies per subclass according to Lavieille and the DFS seems also to differ per subclass. Subclass according to Zanoletti showed comparable treatment strategies and survival outcomes per subclass. CONCLUSION: Our study suggests that the subclass according Lavieille might have added value in clinical practice to improve care of T4‐classified EAC SCC. |
| format | Online Article Text |
| id | pubmed-9541903 |
| institution | National Center for Biotechnology Information |
| language | English |
| publishDate | 2022 |
| publisher | John Wiley & Sons, Inc. |
| record_format | MEDLINE/PubMed |
| spelling | pubmed-95419032022-10-14 Evaluation of subclasses for T4‐classified squamous cell carcinoma of the external auditory canal Nabuurs, Cindy H. Kievit, Wietske Leemans, C. René Smit, Conrad F. G. M. van den Brekel, Michiel W. M. Pauw, Robert J. van der Laan, Bernard F. A. M. Jansen, Jeroen C. Lacko, Martin Braunius, Weibel W. Dai, Chunfu Shi, Xunbei Danesi, Giovanni Bouček, Jan Takes, Robert P. Kunst, Henricus P. M. Head Neck Original Articles BACKGROUND: T4‐classified squamous cell carcinoma (SCC) of external auditory canal (EAC) can potentially involve different anatomical structures, which could translate into different treatment strategies and survival outcomes within one classification. Our aim is to evaluate the clinical added value of T4‐subclasses proposed by Lavieille and by Zanoletti. METHODS: Retrospective data, including patients with primary operated cT4‐classified EAC SCC, was obtained from 12 international hospitals. We subclassified according to the T4‐subclasses. The treatment strategies, disease‐free survival (DFS) and overall survival per subclass were calculated. RESULTS: A total of 130 T4‐classified EAC SCC were included. We found commonly used treatment strategies per subclass according to Lavieille and the DFS seems also to differ per subclass. Subclass according to Zanoletti showed comparable treatment strategies and survival outcomes per subclass. CONCLUSION: Our study suggests that the subclass according Lavieille might have added value in clinical practice to improve care of T4‐classified EAC SCC. John Wiley & Sons, Inc. 2022-05-13 2022-08 /pmc/articles/PMC9541903/ /pubmed/35560966 http://dx.doi.org/10.1002/hed.27082 Text en © 2022 The Authors. Head & Neck published by Wiley Periodicals LLC. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc-nd/4.0/ (https://creativecommons.org/licenses/by-nc-nd/4.0/) License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non‐commercial and no modifications or adaptations are made. |
| spellingShingle | Original Articles Nabuurs, Cindy H. Kievit, Wietske Leemans, C. René Smit, Conrad F. G. M. van den Brekel, Michiel W. M. Pauw, Robert J. van der Laan, Bernard F. A. M. Jansen, Jeroen C. Lacko, Martin Braunius, Weibel W. Dai, Chunfu Shi, Xunbei Danesi, Giovanni Bouček, Jan Takes, Robert P. Kunst, Henricus P. M. Evaluation of subclasses for T4‐classified squamous cell carcinoma of the external auditory canal |
| title | Evaluation of subclasses for T4‐classified squamous cell carcinoma of the external auditory canal |
| title_full | Evaluation of subclasses for T4‐classified squamous cell carcinoma of the external auditory canal |
| title_fullStr | Evaluation of subclasses for T4‐classified squamous cell carcinoma of the external auditory canal |
| title_full_unstemmed | Evaluation of subclasses for T4‐classified squamous cell carcinoma of the external auditory canal |
| title_short | Evaluation of subclasses for T4‐classified squamous cell carcinoma of the external auditory canal |
| title_sort | evaluation of subclasses for t4‐classified squamous cell carcinoma of the external auditory canal |
| topic | Original Articles |
| url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9541903/ https://www.ncbi.nlm.nih.gov/pubmed/35560966 http://dx.doi.org/10.1002/hed.27082 |
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