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Access to dental care and blood pressure profiles in adults with high socioeconomic status

BACKGROUND: Reduced access to dental care may increase cardiovascular risk; however, socioeconomic factors are believed to confound the associations. We hypothesized that the relation persists despite economic wellness and high education, with reduced access to dental care affecting cardiovascular r...

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Autores principales: Del Pinto, Rita, Monaco, Annalisa, Ortu, Eleonora, Czesnikiewicz‐Guzik, Marta, Muñoz Aguilera, Eva, Giannoni, Mario, D'Aiuto, Francesco, Guzik, Tomasz J., Ferri, Claudio, Pietropaoli, Davide
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9542004/
https://www.ncbi.nlm.nih.gov/pubmed/34726790
http://dx.doi.org/10.1002/JPER.21-0439
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author Del Pinto, Rita
Monaco, Annalisa
Ortu, Eleonora
Czesnikiewicz‐Guzik, Marta
Muñoz Aguilera, Eva
Giannoni, Mario
D'Aiuto, Francesco
Guzik, Tomasz J.
Ferri, Claudio
Pietropaoli, Davide
author_facet Del Pinto, Rita
Monaco, Annalisa
Ortu, Eleonora
Czesnikiewicz‐Guzik, Marta
Muñoz Aguilera, Eva
Giannoni, Mario
D'Aiuto, Francesco
Guzik, Tomasz J.
Ferri, Claudio
Pietropaoli, Davide
author_sort Del Pinto, Rita
collection PubMed
description BACKGROUND: Reduced access to dental care may increase cardiovascular risk; however, socioeconomic factors are believed to confound the associations. We hypothesized that the relation persists despite economic wellness and high education, with reduced access to dental care affecting cardiovascular risk at least in part through its effect on blood pressure (BP), possibly mediated by systemic inflammation. METHODS: We first assessed the sociodemographic and clinical characteristics related to last dental visit timing (≤ or >6 months; self‐reported) using national representative cross‐sectional data. Then, the association of last dental visit timing with clinic BP was selectively investigated in highly educated, high income participants, further matched for residual demographic and clinical confounders using propensity score matching (PSM). The mediating effect of systemic inflammation was formally tested. Machine learning was implemented to investigate the added value of dental visits in predicting high BP over the variables included in the Framingham Hypertension Risk Score among individuals without an established diagnosis of hypertension. RESULTS: Of 27,725 participants included in the population analysis, 46% attended a dental visit ≤6 months. In the PSM cohort (n = 2350), last dental visit attendance >6 months was consistently associated with 2 mmHg higher systolic BP (P = 0.001) and with 23 to 35% higher odds of high/uncontrolled BP compared with attendance ≤6 months. Inflammation mildly mediated the association. Access to dental care improved the prediction of high BP by 2%. CONCLUSIONS: Dental care use impacts on BP profiles independent of socioeconomic confounders, possibly through systemic inflammation. Regular dental visits may contribute to preventive medicine.
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spelling pubmed-95420042022-10-14 Access to dental care and blood pressure profiles in adults with high socioeconomic status Del Pinto, Rita Monaco, Annalisa Ortu, Eleonora Czesnikiewicz‐Guzik, Marta Muñoz Aguilera, Eva Giannoni, Mario D'Aiuto, Francesco Guzik, Tomasz J. Ferri, Claudio Pietropaoli, Davide J Periodontol Translational Periodontology BACKGROUND: Reduced access to dental care may increase cardiovascular risk; however, socioeconomic factors are believed to confound the associations. We hypothesized that the relation persists despite economic wellness and high education, with reduced access to dental care affecting cardiovascular risk at least in part through its effect on blood pressure (BP), possibly mediated by systemic inflammation. METHODS: We first assessed the sociodemographic and clinical characteristics related to last dental visit timing (≤ or >6 months; self‐reported) using national representative cross‐sectional data. Then, the association of last dental visit timing with clinic BP was selectively investigated in highly educated, high income participants, further matched for residual demographic and clinical confounders using propensity score matching (PSM). The mediating effect of systemic inflammation was formally tested. Machine learning was implemented to investigate the added value of dental visits in predicting high BP over the variables included in the Framingham Hypertension Risk Score among individuals without an established diagnosis of hypertension. RESULTS: Of 27,725 participants included in the population analysis, 46% attended a dental visit ≤6 months. In the PSM cohort (n = 2350), last dental visit attendance >6 months was consistently associated with 2 mmHg higher systolic BP (P = 0.001) and with 23 to 35% higher odds of high/uncontrolled BP compared with attendance ≤6 months. Inflammation mildly mediated the association. Access to dental care improved the prediction of high BP by 2%. CONCLUSIONS: Dental care use impacts on BP profiles independent of socioeconomic confounders, possibly through systemic inflammation. Regular dental visits may contribute to preventive medicine. John Wiley and Sons Inc. 2021-12-21 2022-07 /pmc/articles/PMC9542004/ /pubmed/34726790 http://dx.doi.org/10.1002/JPER.21-0439 Text en © 2021 The Authors. Journal of Periodontology published by Wiley Periodicals LLC on behalf of American Academy of Periodontology. https://creativecommons.org/licenses/by/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
spellingShingle Translational Periodontology
Del Pinto, Rita
Monaco, Annalisa
Ortu, Eleonora
Czesnikiewicz‐Guzik, Marta
Muñoz Aguilera, Eva
Giannoni, Mario
D'Aiuto, Francesco
Guzik, Tomasz J.
Ferri, Claudio
Pietropaoli, Davide
Access to dental care and blood pressure profiles in adults with high socioeconomic status
title Access to dental care and blood pressure profiles in adults with high socioeconomic status
title_full Access to dental care and blood pressure profiles in adults with high socioeconomic status
title_fullStr Access to dental care and blood pressure profiles in adults with high socioeconomic status
title_full_unstemmed Access to dental care and blood pressure profiles in adults with high socioeconomic status
title_short Access to dental care and blood pressure profiles in adults with high socioeconomic status
title_sort access to dental care and blood pressure profiles in adults with high socioeconomic status
topic Translational Periodontology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9542004/
https://www.ncbi.nlm.nih.gov/pubmed/34726790
http://dx.doi.org/10.1002/JPER.21-0439
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