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Access to dental care and blood pressure profiles in adults with high socioeconomic status
BACKGROUND: Reduced access to dental care may increase cardiovascular risk; however, socioeconomic factors are believed to confound the associations. We hypothesized that the relation persists despite economic wellness and high education, with reduced access to dental care affecting cardiovascular r...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9542004/ https://www.ncbi.nlm.nih.gov/pubmed/34726790 http://dx.doi.org/10.1002/JPER.21-0439 |
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author | Del Pinto, Rita Monaco, Annalisa Ortu, Eleonora Czesnikiewicz‐Guzik, Marta Muñoz Aguilera, Eva Giannoni, Mario D'Aiuto, Francesco Guzik, Tomasz J. Ferri, Claudio Pietropaoli, Davide |
author_facet | Del Pinto, Rita Monaco, Annalisa Ortu, Eleonora Czesnikiewicz‐Guzik, Marta Muñoz Aguilera, Eva Giannoni, Mario D'Aiuto, Francesco Guzik, Tomasz J. Ferri, Claudio Pietropaoli, Davide |
author_sort | Del Pinto, Rita |
collection | PubMed |
description | BACKGROUND: Reduced access to dental care may increase cardiovascular risk; however, socioeconomic factors are believed to confound the associations. We hypothesized that the relation persists despite economic wellness and high education, with reduced access to dental care affecting cardiovascular risk at least in part through its effect on blood pressure (BP), possibly mediated by systemic inflammation. METHODS: We first assessed the sociodemographic and clinical characteristics related to last dental visit timing (≤ or >6 months; self‐reported) using national representative cross‐sectional data. Then, the association of last dental visit timing with clinic BP was selectively investigated in highly educated, high income participants, further matched for residual demographic and clinical confounders using propensity score matching (PSM). The mediating effect of systemic inflammation was formally tested. Machine learning was implemented to investigate the added value of dental visits in predicting high BP over the variables included in the Framingham Hypertension Risk Score among individuals without an established diagnosis of hypertension. RESULTS: Of 27,725 participants included in the population analysis, 46% attended a dental visit ≤6 months. In the PSM cohort (n = 2350), last dental visit attendance >6 months was consistently associated with 2 mmHg higher systolic BP (P = 0.001) and with 23 to 35% higher odds of high/uncontrolled BP compared with attendance ≤6 months. Inflammation mildly mediated the association. Access to dental care improved the prediction of high BP by 2%. CONCLUSIONS: Dental care use impacts on BP profiles independent of socioeconomic confounders, possibly through systemic inflammation. Regular dental visits may contribute to preventive medicine. |
format | Online Article Text |
id | pubmed-9542004 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | John Wiley and Sons Inc. |
record_format | MEDLINE/PubMed |
spelling | pubmed-95420042022-10-14 Access to dental care and blood pressure profiles in adults with high socioeconomic status Del Pinto, Rita Monaco, Annalisa Ortu, Eleonora Czesnikiewicz‐Guzik, Marta Muñoz Aguilera, Eva Giannoni, Mario D'Aiuto, Francesco Guzik, Tomasz J. Ferri, Claudio Pietropaoli, Davide J Periodontol Translational Periodontology BACKGROUND: Reduced access to dental care may increase cardiovascular risk; however, socioeconomic factors are believed to confound the associations. We hypothesized that the relation persists despite economic wellness and high education, with reduced access to dental care affecting cardiovascular risk at least in part through its effect on blood pressure (BP), possibly mediated by systemic inflammation. METHODS: We first assessed the sociodemographic and clinical characteristics related to last dental visit timing (≤ or >6 months; self‐reported) using national representative cross‐sectional data. Then, the association of last dental visit timing with clinic BP was selectively investigated in highly educated, high income participants, further matched for residual demographic and clinical confounders using propensity score matching (PSM). The mediating effect of systemic inflammation was formally tested. Machine learning was implemented to investigate the added value of dental visits in predicting high BP over the variables included in the Framingham Hypertension Risk Score among individuals without an established diagnosis of hypertension. RESULTS: Of 27,725 participants included in the population analysis, 46% attended a dental visit ≤6 months. In the PSM cohort (n = 2350), last dental visit attendance >6 months was consistently associated with 2 mmHg higher systolic BP (P = 0.001) and with 23 to 35% higher odds of high/uncontrolled BP compared with attendance ≤6 months. Inflammation mildly mediated the association. Access to dental care improved the prediction of high BP by 2%. CONCLUSIONS: Dental care use impacts on BP profiles independent of socioeconomic confounders, possibly through systemic inflammation. Regular dental visits may contribute to preventive medicine. John Wiley and Sons Inc. 2021-12-21 2022-07 /pmc/articles/PMC9542004/ /pubmed/34726790 http://dx.doi.org/10.1002/JPER.21-0439 Text en © 2021 The Authors. Journal of Periodontology published by Wiley Periodicals LLC on behalf of American Academy of Periodontology. https://creativecommons.org/licenses/by/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Translational Periodontology Del Pinto, Rita Monaco, Annalisa Ortu, Eleonora Czesnikiewicz‐Guzik, Marta Muñoz Aguilera, Eva Giannoni, Mario D'Aiuto, Francesco Guzik, Tomasz J. Ferri, Claudio Pietropaoli, Davide Access to dental care and blood pressure profiles in adults with high socioeconomic status |
title | Access to dental care and blood pressure profiles in adults with high socioeconomic status |
title_full | Access to dental care and blood pressure profiles in adults with high socioeconomic status |
title_fullStr | Access to dental care and blood pressure profiles in adults with high socioeconomic status |
title_full_unstemmed | Access to dental care and blood pressure profiles in adults with high socioeconomic status |
title_short | Access to dental care and blood pressure profiles in adults with high socioeconomic status |
title_sort | access to dental care and blood pressure profiles in adults with high socioeconomic status |
topic | Translational Periodontology |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9542004/ https://www.ncbi.nlm.nih.gov/pubmed/34726790 http://dx.doi.org/10.1002/JPER.21-0439 |
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