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SARS‐CoV‐2 variants preferentially emerge at intrinsically disordered protein sites helping immune evasion

The SARS‐CoV‐2 pandemic is maintained by the emergence of successive variants, highlighting the flexibility of the protein sequences of the virus. We show that experimentally determined intrinsically disordered regions (IDRs) are abundant in the SARS‐CoV‐2 viral proteins, making up to 28% of disorde...

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Detalles Bibliográficos
Autores principales: Quaglia, Federica, Salladini, Edoardo, Carraro, Marco, Minervini, Giovanni, Tosatto, Silvio C.E., Le Mercier, Philippe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9542094/
https://www.ncbi.nlm.nih.gov/pubmed/35108439
http://dx.doi.org/10.1111/febs.16379