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Druggability Evaluation of the Neuron Derived Orphan Receptor (NOR‐1) Reveals Inverse NOR‐1 Agonists
The neuron derived orphan receptor (NOR‐1, NR4A3) is among the least studied nuclear receptors. Its physiological role and therapeutic potential remain widely elusive which is in part due to the lack of chemical tools that can directly modulate NOR‐1 activity. To probe the possibility of pharmacolog...
Autores principales: | Zaienne, Daniel, Arifi, Silvia, Marschner, Julian A., Heering, Jan, Merk, Daniel |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9542104/ https://www.ncbi.nlm.nih.gov/pubmed/35704774 http://dx.doi.org/10.1002/cmdc.202200259 |
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