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Druggability Evaluation of the Neuron Derived Orphan Receptor (NOR‐1) Reveals Inverse NOR‐1 Agonists

The neuron derived orphan receptor (NOR‐1, NR4A3) is among the least studied nuclear receptors. Its physiological role and therapeutic potential remain widely elusive which is in part due to the lack of chemical tools that can directly modulate NOR‐1 activity. To probe the possibility of pharmacolog...

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Detalles Bibliográficos
Autores principales: Zaienne, Daniel, Arifi, Silvia, Marschner, Julian A., Heering, Jan, Merk, Daniel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9542104/
https://www.ncbi.nlm.nih.gov/pubmed/35704774
http://dx.doi.org/10.1002/cmdc.202200259

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