Cargando…

Transplantation of encapsulated autologous olfactory ensheathing cell populations expressing chondroitinase for spinal cord injury: A safety and feasibility study in companion dogs

Spinal cord injury (SCI) can cause irreversible paralysis, with no regenerative treatment clinically available. Dogs with natural SCI present an established model and can facilitate translation of experimental findings in rodents to people. We conducted a prospective, single arm clinical safety stud...

Descripción completa

Detalles Bibliográficos
Autores principales:	Prager, Jon, Fenn, Joe, Plested, Mark, Escauriaza, Leticia, van der Merwe, Tracy, King, Barbora, Chari, Divya, Wong, Liang‐Fong, Granger, Nicolas
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2022
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9542194/ https://www.ncbi.nlm.nih.gov/pubmed/35686704 http://dx.doi.org/10.1002/term.3328

Ejemplares similares

Transplantation of canine olfactory ensheathing cells producing chondroitinase ABC promotes chondroitin sulphate proteoglycan digestion and axonal sprouting following spinal cord injury
por: Carwardine, Darren, et al.
Publicado: (2017)

Methods of olfactory ensheathing cell harvesting from the olfactory mucosa in dogs
por: Ito, Daisuke, et al.
Publicado: (2019)

CNPase Expression in Olfactory Ensheathing Cells
por: Radtke, Christine, et al.
Publicado: (2011)

Olfactory ensheathing cells and neuropathic pain
por: Liu, Ji-peng, et al.
Publicado: (2023)

Autologous olfactory ensheathing cell transplantation in human paraplegia: a 3-year clinical trial
por: Mackay-Sim, A., et al.
Publicado: (2008)

Harvesting of olfactory ensheathing cells for autologous transplantation into the spinal cord injury. Its complexity in dogs
por: Salazar, Ignacio, et al.
Publicado: (2015)

Olfactory Ensheathing Cell Tumor Arising from the Olfactory Mucosa
por: Ogino-Nishimura, Eriko, et al.
Publicado: (2012)

Olfactory ensheathing cells in facial nerve regeneration()
por: Li, Manyi, et al.
Publicado: (2018)

Common olfactory ensheathing glial markers in the developing human olfactory system
por: Oprych, Karen, et al.
Publicado: (2016)

A 3-Dimensional Printed Patient-Specific Surgical Guide to Facilitate Transsphenoidal Hypophysectomy in Dogs
por: Escauriaza, Leticia, et al.
Publicado: (2022)

Why are olfactory ensheathing cell tumors so rare?
por: Murtaza, Mariyam, et al.
Publicado: (2019)

Zika virus leads to olfactory disorders in mice by targeting olfactory ensheathing cells
por: Zhou, Jia, et al.
Publicado: (2023)

Effects of Different Sera Conditions on Olfactory Ensheathing Cells in Vitro
por: Lu, Meng, et al.
Publicado: (2014)

Influence of Biphasic Stimulation on Olfactory Ensheathing Cells for Neuroprosthetic Devices
por: Hassarati, Rachelle T., et al.
Publicado: (2016)

Direct neuronal reprogramming of olfactory ensheathing cells for CNS repair
por: Sun, Xiu, et al.
Publicado: (2019)

Gene and protein expression profiles of olfactory ensheathing cells from olfactory bulb versus olfactory mucosa
por: Lan, Yuan-Xiang, et al.
Publicado: (2021)

Calponin is expressed by subpopulations of connective tissue cells but not olfactory ensheathing cells in the neonatal olfactory mucosa
por: Tomé, Mercedes, et al.
Publicado: (2007)

Targeting chondroitinase ABC to axons enhances the ability of chondroitinase to promote neurite outgrowth and sprouting
por: Day, Priscilla, et al.
Publicado: (2020)

Olfactory Ensheathing Glia: Drivers of Axonal Regeneration in the Central Nervous System?
por: Teresa Moreno-Flores, M., et al.
Publicado: (2002)

Streptococcus pneumoniae resists intracellular killing by olfactory ensheathing cells but not by microglia
por: Macedo-Ramos, Hugo, et al.
Publicado: (2016)

Olfactory Ensheathing Cells for Spinal Cord Injury: Sniffing Out the Issues
por: Yao, R., et al.
Publicado: (2018)

The Immunological Roles of Olfactory Ensheathing Cells in the Treatment of Spinal Cord Injury
por: Jiang, Yizhen, et al.
Publicado: (2022)

Designing Olfactory Ensheathing Cell Transplantation Therapies: Influence of Cell Microenvironment
por: Murtaza, Mariyam, et al.
Publicado: (2022)

Olfactory ensheathing cells abutting the embryonic olfactory bulb express Frzb, whose deletion disrupts olfactory axon targeting
por: Rich, Constance A., et al.
Publicado: (2018)

Olfactory ensheathing glia are required for embryonic olfactory axon targeting and the migration of gonadotropin-releasing hormone neurons
por: Barraud, Perrine, et al.
Publicado: (2013)

The culture of olfactory ensheathing cells (OECs)—a distinct glial cell type
por: Higginson, Jennifer R., et al.
Publicado: (2011)

Potential of Olfactory Ensheathing Cells from Different Sources for Spinal Cord Repair
por: Mayeur, Anne, et al.
Publicado: (2013)

Olfactory Ensheathing Cells Express α7 Integrin to Mediate Their Migration on Laminin
por: Ingram, Norianne T., et al.
Publicado: (2016)

Characteristics of olfactory ensheathing cells and microarray analysis in Tupaia belangeri (Wagner, 1841)
por: Lin, Na, et al.
Publicado: (2019)

Reconstruction of the Damaged Dorsal Root Entry Zone by Transplantation of Olfactory Ensheathing Cells
por: Collins, Andrew, et al.
Publicado: (2019)

AMPA Receptor-Mediated Ca(2+) Transients in Mouse Olfactory Ensheathing Cells
por: Beiersdorfer, Antonia, et al.
Publicado: (2019)

Neurotrophic and immunomodulatory effects of olfactory ensheathing cells as a strategy for neuroprotection and regeneration
por: Denaro, Simona, et al.
Publicado: (2022)

Transplantation of Cryopreserved Olfactory Ensheathing Cells Restores Loss of Functions in an Experimental Model
por: Minkelyte, Kamile, et al.
Publicado: (2023)

Generation of Magnetized Olfactory Ensheathing Cells for Regenerative Studies in the Central and Peripheral Nervous Tissue
por: Riggio, Cristina, et al.
Publicado: (2013)

Low-Dose Curcumin Stimulates Proliferation, Migration and Phagocytic Activity of Olfactory Ensheathing Cells
por: Tello Velasquez, Johana, et al.
Publicado: (2014)

Olfactory ensheathing cells for spinal cord repair: crucial differences between subpopulations of the glia
por: Ekberg, Jenny A.K., et al.
Publicado: (2015)

Evidence for a Notch1‐mediated transition during olfactory ensheathing cell development
por: Miller, Sophie R., et al.
Publicado: (2016)

Enhancing the Therapeutic Potential of Olfactory Ensheathing Cells in Spinal Cord Repair Using Neurotrophins
por: Wright, A. A., et al.
Publicado: (2018)

Biological effects different diameters of Tussah silk fibroin nanofibers on olfactory ensheathing cells
por: Wu, Peng, et al.
Publicado: (2019)

Olfactory ensheathing cells travel their natural nasal pathway to deliver therapeutics to brain tumors
por: Carvalho, Litia A., et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_k6qaibl7264oi498i65fgvh8v0