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A High‐Throughput Continuous Spectroscopic Assay to Measure the Activity of Natural Product Methyltransferases

Natural product methyltransferases (NPMTs) represent an emerging class of enzymes that can be of great use for the structural and functional diversification of bioactive compounds, such as the strategic modification of C‐, N‐, O‐ and S‐moieties. To assess the activity and the substrate scope of the...

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Detalles Bibliográficos
Autores principales: Simon‐Baram, Hadas, Roth, Steffen, Niedermayer, Christina, Huber, Patricia, Speck, Melanie, Diener, Julia, Richter, Michael, Bershtein, Shimon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9542197/
https://www.ncbi.nlm.nih.gov/pubmed/35785511
http://dx.doi.org/10.1002/cbic.202200162