The protective gene dose effect of the APOE ε2 allele on gray matter volume in cognitively unimpaired individuals

INTRODUCTION: Harboring two copies of the apolipoprotein E (APOE) ε2 allele strongly protects against Alzheimer's disease (AD). However, the effect of this genotype on gray matter (GM) volume in cognitively unimpaired individuals has not yet been described. METHODS: Multicenter brain magnetic r...

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Detalles Bibliográficos
Autores principales: Salvadó, Gemma, Ferreira, Daniel, Operto, Grégory, Cumplido‐Mayoral, Irene, Arenaza‐Urquijo, Eider M., Cacciaglia, Raffaele, Falcon, Carles, Vilor‐Tejedor, Natàlia, Minguillon, Carolina, Groot, Colin, van der Flier, Wiesje M., Barkhof, Frederik, Scheltens, Philip, Ossenkoppele, Rik, Kern, Silke, Zettergren, Anna, Skoog, Ingmar, Hort, Jakub, Stomrud, Erik, van Westen, Danielle, Hansson, Oskar, Molinuevo, José Luis, Wahlund, Lars‐Olof, Westman, Eric, Gispert, Juan Domingo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
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Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9542211/
https://www.ncbi.nlm.nih.gov/pubmed/34877786
http://dx.doi.org/10.1002/alz.12487

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9542211/
https://www.ncbi.nlm.nih.gov/pubmed/34877786
http://dx.doi.org/10.1002/alz.12487

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