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Increased COX‐2 after ureter obstruction attenuates fibrosis and is associated with EP(2) receptor upregulation in mouse and human kidney

AIM: Cyclooxygenase‐2 (COX‐2) activity protects against oxidative stress and apoptosis early in experimental kidney injury. The present study was designed to test the hypothesis that COX‐2 activity attenuates fibrosis and preserves microvasculature in injured kidney. The murine unilateral ureteral‐o...

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Detalles Bibliográficos
Autores principales:	Tofteng, Signe S., Nilsson, Line, Mogensen, Amalie K., Nørregaard, Rikke, Nüsing, Rolf, Diatchikhine, Mikhail, Lund, Lars, Bistrup, Claus, Jensen, Boye L., Madsen, Kirsten
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2022
Materias:	Renal Physiology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9542224/ https://www.ncbi.nlm.nih.gov/pubmed/35543087 http://dx.doi.org/10.1111/apha.13828

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