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Developing services to support the delivery of care to people with early‐onset type 2 diabetes

Early‐onset type 2 diabetes occurring in childhood or early adulthood carries a significant excess burden of microvascular diabetes complications, cardiovascular disease and premature death, compared to later onset type 2 diabetes along with adverse pregnancy outcomes in women of child‐bearing age....

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Autores principales: Misra, Shivani, Gable, David, Khunti, Kamlesh, Barron, Emma, Young, Bob, Kar, Partha, Valabhji, Jonathan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9542364/
https://www.ncbi.nlm.nih.gov/pubmed/35900910
http://dx.doi.org/10.1111/dme.14927
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author Misra, Shivani
Gable, David
Khunti, Kamlesh
Barron, Emma
Young, Bob
Kar, Partha
Valabhji, Jonathan
author_facet Misra, Shivani
Gable, David
Khunti, Kamlesh
Barron, Emma
Young, Bob
Kar, Partha
Valabhji, Jonathan
author_sort Misra, Shivani
collection PubMed
description Early‐onset type 2 diabetes occurring in childhood or early adulthood carries a significant excess burden of microvascular diabetes complications, cardiovascular disease and premature death, compared to later onset type 2 diabetes along with adverse pregnancy outcomes in women of child‐bearing age. National audit data in England reveal that 122,780 individuals under the age of 40 years are currently living with type 2 diabetes, with an over‐representation of people from minority ethnicities and those in the most socioeconomically deprived quintiles. A diagnosis of type 2 diabetes earlier in life poses some unique challenges to healthcare providers that are not routinely encountered when type 2 diabetes presents later. These include; (1) the need to ensure correct diabetes classification in an age group that carries a higher probability of other types of diabetes, (2) overcoming difficulties in engaging with individuals who are of working age or in full‐time education, (3) appreciating and addressing the lower attainment of diabetes treatment targets and (4) proactively supporting women of child‐bearing age to optimise their future pregnancy outcomes through better preparation for pregnancy, including achieving optimum glycaemic control at the time of conception. Meanwhile, approaches to prevent type 2 diabetes in younger age groups are challenged by difficulties in identifying those at highest risk, by poorer attendance at lifestyle interventions to prevent or delay the onset of type 2 diabetes and by attenuation of associated weight loss in those that do attend. In this article, we discuss the importance of recognising and addressing the distinct challenges in delivering healthcare to those with early‐onset type 2 diabetes, the greater challenges in preventing type 2 diabetes at younger ages, and key components of strategies that might address these challenges to drive improvements in pregnancy outcomes, microvascular and cardiovascular outcomes.
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spelling pubmed-95423642022-10-14 Developing services to support the delivery of care to people with early‐onset type 2 diabetes Misra, Shivani Gable, David Khunti, Kamlesh Barron, Emma Young, Bob Kar, Partha Valabhji, Jonathan Diabet Med Review Early‐onset type 2 diabetes occurring in childhood or early adulthood carries a significant excess burden of microvascular diabetes complications, cardiovascular disease and premature death, compared to later onset type 2 diabetes along with adverse pregnancy outcomes in women of child‐bearing age. National audit data in England reveal that 122,780 individuals under the age of 40 years are currently living with type 2 diabetes, with an over‐representation of people from minority ethnicities and those in the most socioeconomically deprived quintiles. A diagnosis of type 2 diabetes earlier in life poses some unique challenges to healthcare providers that are not routinely encountered when type 2 diabetes presents later. These include; (1) the need to ensure correct diabetes classification in an age group that carries a higher probability of other types of diabetes, (2) overcoming difficulties in engaging with individuals who are of working age or in full‐time education, (3) appreciating and addressing the lower attainment of diabetes treatment targets and (4) proactively supporting women of child‐bearing age to optimise their future pregnancy outcomes through better preparation for pregnancy, including achieving optimum glycaemic control at the time of conception. Meanwhile, approaches to prevent type 2 diabetes in younger age groups are challenged by difficulties in identifying those at highest risk, by poorer attendance at lifestyle interventions to prevent or delay the onset of type 2 diabetes and by attenuation of associated weight loss in those that do attend. In this article, we discuss the importance of recognising and addressing the distinct challenges in delivering healthcare to those with early‐onset type 2 diabetes, the greater challenges in preventing type 2 diabetes at younger ages, and key components of strategies that might address these challenges to drive improvements in pregnancy outcomes, microvascular and cardiovascular outcomes. John Wiley and Sons Inc. 2022-08-23 2022-10 /pmc/articles/PMC9542364/ /pubmed/35900910 http://dx.doi.org/10.1111/dme.14927 Text en © 2022 The Authors. Diabetic Medicine published by John Wiley & Sons Ltd on behalf of Diabetes UK. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc-nd/4.0/ (https://creativecommons.org/licenses/by-nc-nd/4.0/) License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non‐commercial and no modifications or adaptations are made.
spellingShingle Review
Misra, Shivani
Gable, David
Khunti, Kamlesh
Barron, Emma
Young, Bob
Kar, Partha
Valabhji, Jonathan
Developing services to support the delivery of care to people with early‐onset type 2 diabetes
title Developing services to support the delivery of care to people with early‐onset type 2 diabetes
title_full Developing services to support the delivery of care to people with early‐onset type 2 diabetes
title_fullStr Developing services to support the delivery of care to people with early‐onset type 2 diabetes
title_full_unstemmed Developing services to support the delivery of care to people with early‐onset type 2 diabetes
title_short Developing services to support the delivery of care to people with early‐onset type 2 diabetes
title_sort developing services to support the delivery of care to people with early‐onset type 2 diabetes
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9542364/
https://www.ncbi.nlm.nih.gov/pubmed/35900910
http://dx.doi.org/10.1111/dme.14927
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