Unified Approach to Diverse Fused Fragments via Catalytic Dehydrative Cyclization

A range of highly functionalized polycyclic fragments have been synthesized, employing a catalytic dehydrative cyclization. A range of nucleophiles are shown to be successful, with the reaction producing numerous high value motifs.

Detalles Bibliográficos
Autores principales: Basson, Ashley J., Halcovitch, Nathan R., McLaughlin, Mark G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9542485/
https://www.ncbi.nlm.nih.gov/pubmed/35642626
http://dx.doi.org/10.1002/chem.202201107
Descripción
Sumario:A range of highly functionalized polycyclic fragments have been synthesized, employing a catalytic dehydrative cyclization. A range of nucleophiles are shown to be successful, with the reaction producing numerous high value motifs.

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