Unified Approach to Diverse Fused Fragments via Catalytic Dehydrative Cyclization

A range of highly functionalized polycyclic fragments have been synthesized, employing a catalytic dehydrative cyclization. A range of nucleophiles are shown to be successful, with the reaction producing numerous high value motifs.

Detalles Bibliográficos
Autores principales: Basson, Ashley J., Halcovitch, Nathan R., McLaughlin, Mark G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9542485/
https://www.ncbi.nlm.nih.gov/pubmed/35642626
http://dx.doi.org/10.1002/chem.202201107
_version_ 1784804160823099392
author Basson, Ashley J.
Halcovitch, Nathan R.
McLaughlin, Mark G.
author_facet Basson, Ashley J.
Halcovitch, Nathan R.
McLaughlin, Mark G.
author_sort Basson, Ashley J.
collection PubMed
description A range of highly functionalized polycyclic fragments have been synthesized, employing a catalytic dehydrative cyclization. A range of nucleophiles are shown to be successful, with the reaction producing numerous high value motifs.
format Online
Article
Text
id pubmed-9542485
institution National Center for Biotechnology Information
language English
publishDate 2022
publisher John Wiley and Sons Inc.
record_format MEDLINE/PubMed
spelling pubmed-95424852022-10-14 Unified Approach to Diverse Fused Fragments via Catalytic Dehydrative Cyclization Basson, Ashley J. Halcovitch, Nathan R. McLaughlin, Mark G. Chemistry Research Articles A range of highly functionalized polycyclic fragments have been synthesized, employing a catalytic dehydrative cyclization. A range of nucleophiles are shown to be successful, with the reaction producing numerous high value motifs. John Wiley and Sons Inc. 2022-07-04 2022-08-26 /pmc/articles/PMC9542485/ /pubmed/35642626 http://dx.doi.org/10.1002/chem.202201107 Text en © 2022 The Authors. Chemistry - A European Journal published by Wiley-VCH GmbH https://creativecommons.org/licenses/by/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research Articles
Basson, Ashley J.
Halcovitch, Nathan R.
McLaughlin, Mark G.
Unified Approach to Diverse Fused Fragments via Catalytic Dehydrative Cyclization
title Unified Approach to Diverse Fused Fragments via Catalytic Dehydrative Cyclization
title_full Unified Approach to Diverse Fused Fragments via Catalytic Dehydrative Cyclization
title_fullStr Unified Approach to Diverse Fused Fragments via Catalytic Dehydrative Cyclization
title_full_unstemmed Unified Approach to Diverse Fused Fragments via Catalytic Dehydrative Cyclization
title_short Unified Approach to Diverse Fused Fragments via Catalytic Dehydrative Cyclization
title_sort unified approach to diverse fused fragments via catalytic dehydrative cyclization
topic Research Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9542485/
https://www.ncbi.nlm.nih.gov/pubmed/35642626
http://dx.doi.org/10.1002/chem.202201107
work_keys_str_mv AT bassonashleyj unifiedapproachtodiversefusedfragmentsviacatalyticdehydrativecyclization
AT halcovitchnathanr unifiedapproachtodiversefusedfragmentsviacatalyticdehydrativecyclization
AT mclaughlinmarkg unifiedapproachtodiversefusedfragmentsviacatalyticdehydrativecyclization

Ejemplares similares