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Surgical treatment of spasticity: intrathecal baclofen pump implantation under subarachnoid block

Most patients with spasticity, rigidity, and other symptoms of the upper motor neuron syndrome respond effectively to surgical treatment with an intrathecal baclofen pump when their symptoms become intractable to nonsurgical measures. Baclofen administered into the lumbar subarachnoid space produces...

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Detalles Bibliográficos
Autores principales: Scerrati, Alba, De Bonis, Pasquale, Norri, Nicolò, Cavallo, Michele Alessandro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association of Neurological Surgeons 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9542496/
https://www.ncbi.nlm.nih.gov/pubmed/36285267
http://dx.doi.org/10.3171/2020.7.FOCVID2021
Descripción
Sumario:Most patients with spasticity, rigidity, and other symptoms of the upper motor neuron syndrome respond effectively to surgical treatment with an intrathecal baclofen pump when their symptoms become intractable to nonsurgical measures. Baclofen administered into the lumbar subarachnoid space produces a locally high concentration at the spinal level and a low concentration supraspinally, avoiding most of the central side effects associated with a high oral dose, such as drowsiness and confusion. The aim of surgical treatment is to provide the appropriate volume and concentration of the drug in the subarachnoid space, avoiding the main surgical complications, that is, infections, skin erosion, and catheter displacement. The video can be found here: https://youtu.be/HetelPwwwak