Cargando…

Microsurgical DREZ lesions for the control of cancer-related pain

Pain in patients with cancer is a major problem, and sometimes it is necessary to surgically interrupt pain pathways to effectively control refractory pain. Surgical lesion of the dorsal root entry zone (DREZ) was first performed in 1972 for the treatment of pain related to a Pancoast-Tobias tumor....

Descripción completa

Detalles Bibliográficos
Autores principales: Mazzucchi, Edoardo, Brinzeu, Andrei, Mertens, Patrick, Sindou, Marc
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association of Neurological Surgeons 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9542504/
https://www.ncbi.nlm.nih.gov/pubmed/36285266
http://dx.doi.org/10.3171/2020.7.FOCVID2033
_version_ 1784804165435785216
author Mazzucchi, Edoardo
Brinzeu, Andrei
Mertens, Patrick
Sindou, Marc
author_facet Mazzucchi, Edoardo
Brinzeu, Andrei
Mertens, Patrick
Sindou, Marc
author_sort Mazzucchi, Edoardo
collection PubMed
description Pain in patients with cancer is a major problem, and sometimes it is necessary to surgically interrupt pain pathways to effectively control refractory pain. Surgical lesion of the dorsal root entry zone (DREZ) was first performed in 1972 for the treatment of pain related to a Pancoast-Tobias tumor. The rationale of DREZotomy is to preferentially interrupt the nociceptive inputs in the lateral part of the DREZ and the ventrolateral (excitatory) part of the dorsal horn. Microsurgical DREZotomy is one technique for DREZ lesioning that is suited for tailored control of pain in patients in good general condition who are experiencing pain in a well-defined territory. The video can be found here: https://youtu.be/JtLQDP7gYSQ
format Online
Article
Text
id pubmed-9542504
institution National Center for Biotechnology Information
language English
publishDate 2020
publisher American Association of Neurological Surgeons
record_format MEDLINE/PubMed
spelling pubmed-95425042022-10-24 Microsurgical DREZ lesions for the control of cancer-related pain Mazzucchi, Edoardo Brinzeu, Andrei Mertens, Patrick Sindou, Marc Neurosurg Focus Video Article Pain in patients with cancer is a major problem, and sometimes it is necessary to surgically interrupt pain pathways to effectively control refractory pain. Surgical lesion of the dorsal root entry zone (DREZ) was first performed in 1972 for the treatment of pain related to a Pancoast-Tobias tumor. The rationale of DREZotomy is to preferentially interrupt the nociceptive inputs in the lateral part of the DREZ and the ventrolateral (excitatory) part of the dorsal horn. Microsurgical DREZotomy is one technique for DREZ lesioning that is suited for tailored control of pain in patients in good general condition who are experiencing pain in a well-defined territory. The video can be found here: https://youtu.be/JtLQDP7gYSQ American Association of Neurological Surgeons 2020-10-01 /pmc/articles/PMC9542504/ /pubmed/36285266 http://dx.doi.org/10.3171/2020.7.FOCVID2033 Text en © 2020 The Authors https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the CC BY-NC-ND license (http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) ).
spellingShingle Article
Mazzucchi, Edoardo
Brinzeu, Andrei
Mertens, Patrick
Sindou, Marc
Microsurgical DREZ lesions for the control of cancer-related pain
title Microsurgical DREZ lesions for the control of cancer-related pain
title_full Microsurgical DREZ lesions for the control of cancer-related pain
title_fullStr Microsurgical DREZ lesions for the control of cancer-related pain
title_full_unstemmed Microsurgical DREZ lesions for the control of cancer-related pain
title_short Microsurgical DREZ lesions for the control of cancer-related pain
title_sort microsurgical drez lesions for the control of cancer-related pain
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9542504/
https://www.ncbi.nlm.nih.gov/pubmed/36285266
http://dx.doi.org/10.3171/2020.7.FOCVID2033
work_keys_str_mv AT mazzucchiedoardo microsurgicaldrezlesionsforthecontrolofcancerrelatedpain
AT brinzeuandrei microsurgicaldrezlesionsforthecontrolofcancerrelatedpain
AT mertenspatrick microsurgicaldrezlesionsforthecontrolofcancerrelatedpain
AT sindoumarc microsurgicaldrezlesionsforthecontrolofcancerrelatedpain