Fast-tracking antibody maturation using a B cell-based display system

Affinity maturation, an essential component of antibody engineering, is crucial for developing therapeutic antibodies. Cell display system coupled with somatic hypermutation (SHM) initiated by activation-induced cytidine deaminase (AID) is a commonly used technique for affinity maturation. AID intro...

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Detalles Bibliográficos
Autores principales: Masuda, Hitomi, Sawada, Atsushi, Hashimoto, Shu-ichi, Tamai, Kanako, Lin, Ke-Yi, Harigai, Naoto, Kurosawa, Kohei, Ohta, Kunihiro, Seo, Hidetaka, Itou, Hiroshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2022
Materias:
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Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9542628/
https://www.ncbi.nlm.nih.gov/pubmed/36202784
http://dx.doi.org/10.1080/19420862.2022.2122275

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