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KRAS, NRAS, BRAF, PIK3CA, and AKT1 signatures in colorectal cancer patients in south-eastern Romania

Somatic mutations in the oncogenes of the epidermal growth factor receptor signaling pathway play vital roles in colorectal carcinogenesis and have been closely linked with clinical resistance to monoclonal therapy. In this study, we have analyzed the mutation frequencies of 5 genes and compared the...

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Detalles Bibliográficos
Autores principales:	Brinzan, Costel Stelian, Aschie, Mariana, Cozaru, Georgeta Camelia, Deacu, Mariana, Dumitru, Eugen, Burlacu, Ionut, Mitroi, Anca
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Lippincott Williams & Wilkins 2022
Materias:	4500
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9542653/ https://www.ncbi.nlm.nih.gov/pubmed/36221415 http://dx.doi.org/10.1097/MD.0000000000030979

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