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KRAS, NRAS, BRAF, PIK3CA, and AKT1 signatures in colorectal cancer patients in south-eastern Romania
Somatic mutations in the oncogenes of the epidermal growth factor receptor signaling pathway play vital roles in colorectal carcinogenesis and have been closely linked with clinical resistance to monoclonal therapy. In this study, we have analyzed the mutation frequencies of 5 genes and compared the...
Autores principales: | Brinzan, Costel Stelian, Aschie, Mariana, Cozaru, Georgeta Camelia, Deacu, Mariana, Dumitru, Eugen, Burlacu, Ionut, Mitroi, Anca |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Lippincott Williams & Wilkins
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9542653/ https://www.ncbi.nlm.nih.gov/pubmed/36221415 http://dx.doi.org/10.1097/MD.0000000000030979 |
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