Cargando…

Treatments targeting autophagy ameliorate the age-related macular degeneration phenotype in mice lacking APOE (apolipoprotein E)

Age-related macular degeneration (AMD) is a leading cause of vision loss with recent evidence indicating an important role for macroautophagy/autophagy in disease progression. In this study we investigate the efficacy of targeting autophagy for slowing dysfunction in a mouse model with features of e...

Descripción completa

Detalles Bibliográficos
Autores principales: Vessey, Kirstan A, Jobling, Andrew I, Tran, Mai X., Wang, Anna Y., Greferath, Ursula, Fletcher, Erica L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9542759/
https://www.ncbi.nlm.nih.gov/pubmed/35196199
http://dx.doi.org/10.1080/15548627.2022.2034131