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Treatments targeting autophagy ameliorate the age-related macular degeneration phenotype in mice lacking APOE (apolipoprotein E)
Age-related macular degeneration (AMD) is a leading cause of vision loss with recent evidence indicating an important role for macroautophagy/autophagy in disease progression. In this study we investigate the efficacy of targeting autophagy for slowing dysfunction in a mouse model with features of e...
Autores principales: | Vessey, Kirstan A, Jobling, Andrew I, Tran, Mai X., Wang, Anna Y., Greferath, Ursula, Fletcher, Erica L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Taylor & Francis
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9542759/ https://www.ncbi.nlm.nih.gov/pubmed/35196199 http://dx.doi.org/10.1080/15548627.2022.2034131 |
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