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Reference intervals of complete blood count parameters for individuals aged 80 to 89 years in Guizhou, China: A STROBE-compliant retrospective study

The reference intervals of complete blood count (CBC) parameters were commonly based on healthy individuals aged 20 to 79 years. However, these values are not optimal for correct clinical diagnosis in older individuals (e.g., 80–89 years). Although the reference intervals for this age group have bee...

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Autores principales: Long, Jinlie, Wang, Xiuhong, Yuan, Jianbo, Yang, Jianru, Zhou, Jie, Chen, Yuan, Hu, Enxi, Zhou, Yuanzhong, Min, Xun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9542839/
https://www.ncbi.nlm.nih.gov/pubmed/36221361
http://dx.doi.org/10.1097/MD.0000000000030859
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author Long, Jinlie
Wang, Xiuhong
Yuan, Jianbo
Yang, Jianru
Zhou, Jie
Chen, Yuan
Hu, Enxi
Zhou, Yuanzhong
Min, Xun
author_facet Long, Jinlie
Wang, Xiuhong
Yuan, Jianbo
Yang, Jianru
Zhou, Jie
Chen, Yuan
Hu, Enxi
Zhou, Yuanzhong
Min, Xun
author_sort Long, Jinlie
collection PubMed
description The reference intervals of complete blood count (CBC) parameters were commonly based on healthy individuals aged 20 to 79 years. However, these values are not optimal for correct clinical diagnosis in older individuals (e.g., 80–89 years). Although the reference intervals for this age group have been reported in China, there is no population-based report in Guizhou province. A total of 481 healthy adults (238 males and 243 females) aged 80 to 89 years were recruited from Affiliated Hospital of Zunyi Medical University in Guizhou. The CBC parameters were detected by Sysmex XN-9000 automatic hematology analyzer. The reference intervals of the components were analyzed according to the guidelines of International Federation of Clinical Chemistry. This study reported the reference intervals of CBC parameters. There were significant differences were examined in some reference intervals between the different gender groups, especially for RBC-related parameters. Compared with national standards, the most of all conventional reference intervals for CBC parameters were decreased. The present study provided the local reference intervals of CBC parameters for individuals aged 80 to 89 years in Guizhou, China. Some of our results were sex-specific, and most of our results show lower values while comparing with commonly used reference intervals in China. Therefore, more attentions should be paid to these differences, and accurate reference intervals will facilitate clinical diagnosis and decision-making in these populations.
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spelling pubmed-95428392022-10-11 Reference intervals of complete blood count parameters for individuals aged 80 to 89 years in Guizhou, China: A STROBE-compliant retrospective study Long, Jinlie Wang, Xiuhong Yuan, Jianbo Yang, Jianru Zhou, Jie Chen, Yuan Hu, Enxi Zhou, Yuanzhong Min, Xun Medicine (Baltimore) 3700 The reference intervals of complete blood count (CBC) parameters were commonly based on healthy individuals aged 20 to 79 years. However, these values are not optimal for correct clinical diagnosis in older individuals (e.g., 80–89 years). Although the reference intervals for this age group have been reported in China, there is no population-based report in Guizhou province. A total of 481 healthy adults (238 males and 243 females) aged 80 to 89 years were recruited from Affiliated Hospital of Zunyi Medical University in Guizhou. The CBC parameters were detected by Sysmex XN-9000 automatic hematology analyzer. The reference intervals of the components were analyzed according to the guidelines of International Federation of Clinical Chemistry. This study reported the reference intervals of CBC parameters. There were significant differences were examined in some reference intervals between the different gender groups, especially for RBC-related parameters. Compared with national standards, the most of all conventional reference intervals for CBC parameters were decreased. The present study provided the local reference intervals of CBC parameters for individuals aged 80 to 89 years in Guizhou, China. Some of our results were sex-specific, and most of our results show lower values while comparing with commonly used reference intervals in China. Therefore, more attentions should be paid to these differences, and accurate reference intervals will facilitate clinical diagnosis and decision-making in these populations. Lippincott Williams & Wilkins 2022-10-07 /pmc/articles/PMC9542839/ /pubmed/36221361 http://dx.doi.org/10.1097/MD.0000000000030859 Text en Copyright © 2022 the Author(s). Published by Wolters Kluwer Health, Inc. https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the Creative Commons Attribution License 4.0 (CCBY) (https://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle 3700
Long, Jinlie
Wang, Xiuhong
Yuan, Jianbo
Yang, Jianru
Zhou, Jie
Chen, Yuan
Hu, Enxi
Zhou, Yuanzhong
Min, Xun
Reference intervals of complete blood count parameters for individuals aged 80 to 89 years in Guizhou, China: A STROBE-compliant retrospective study
title Reference intervals of complete blood count parameters for individuals aged 80 to 89 years in Guizhou, China: A STROBE-compliant retrospective study
title_full Reference intervals of complete blood count parameters for individuals aged 80 to 89 years in Guizhou, China: A STROBE-compliant retrospective study
title_fullStr Reference intervals of complete blood count parameters for individuals aged 80 to 89 years in Guizhou, China: A STROBE-compliant retrospective study
title_full_unstemmed Reference intervals of complete blood count parameters for individuals aged 80 to 89 years in Guizhou, China: A STROBE-compliant retrospective study
title_short Reference intervals of complete blood count parameters for individuals aged 80 to 89 years in Guizhou, China: A STROBE-compliant retrospective study
title_sort reference intervals of complete blood count parameters for individuals aged 80 to 89 years in guizhou, china: a strobe-compliant retrospective study
topic 3700
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9542839/
https://www.ncbi.nlm.nih.gov/pubmed/36221361
http://dx.doi.org/10.1097/MD.0000000000030859
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