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Progressive stages of dysmetabolism are associated with impaired biological features of human cardiac stromal cells mediated by the oxidative state and autophagy

Cardiac stromal cells (CSCs) are the main players in fibrosis. Dysmetabolic conditions (metabolic syndrome—MetS, and type 2 diabetes mellitus—DM2) are strong pathogenetic contributors to cardiac fibrosis. Moreover, modulation of the oxidative state (OxSt) and autophagy is a fundamental function affe...

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Detalles Bibliográficos
Autores principales: Pagano, Francesca, Picchio, Vittorio, Bordin, Antonella, Cavarretta, Elena, Nocella, Cristina, Cozzolino, Claudia, Floris, Erica, Angelini, Francesco, Sordano, Alessia, Peruzzi, Mariangela, Miraldi, Fabio, Biondi‐Zoccai, Giuseppe, De Falco, Elena, Carnevale, Roberto, Sciarretta, Sebastiano, Frati, Giacomo, Chimenti, Isotta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Ltd 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9542980/
https://www.ncbi.nlm.nih.gov/pubmed/35751644
http://dx.doi.org/10.1002/path.5985