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Progressive stages of dysmetabolism are associated with impaired biological features of human cardiac stromal cells mediated by the oxidative state and autophagy
Cardiac stromal cells (CSCs) are the main players in fibrosis. Dysmetabolic conditions (metabolic syndrome—MetS, and type 2 diabetes mellitus—DM2) are strong pathogenetic contributors to cardiac fibrosis. Moreover, modulation of the oxidative state (OxSt) and autophagy is a fundamental function affe...
Autores principales: | Pagano, Francesca, Picchio, Vittorio, Bordin, Antonella, Cavarretta, Elena, Nocella, Cristina, Cozzolino, Claudia, Floris, Erica, Angelini, Francesco, Sordano, Alessia, Peruzzi, Mariangela, Miraldi, Fabio, Biondi‐Zoccai, Giuseppe, De Falco, Elena, Carnevale, Roberto, Sciarretta, Sebastiano, Frati, Giacomo, Chimenti, Isotta |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley & Sons, Ltd
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9542980/ https://www.ncbi.nlm.nih.gov/pubmed/35751644 http://dx.doi.org/10.1002/path.5985 |
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