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Evaluating the Impact of Ionization Chamber-Specific Beam Quality Correction Factor in Dosimetry of Filtered and Unfiltered Photon Beams

AIM: The response of ionization chamber changes when used at beam quality Q which is different from beam quality Q(o) (usually (60)Co) that was used at the time of its calibration. Hence, one needs to apply beam quality correction factor (k(Q, Qo)) during dosimetric measurements. However, k(Q, Qo) d...

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Autores principales: Sharma, Richa, Sharma, Sunil Dutt, Agarwal, Priyanka, Avasthi, Devesh Kumar, Verma, Rohit
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer - Medknow 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9542991/
https://www.ncbi.nlm.nih.gov/pubmed/36212211
http://dx.doi.org/10.4103/jmp.jmp_101_21
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author Sharma, Richa
Sharma, Sunil Dutt
Agarwal, Priyanka
Avasthi, Devesh Kumar
Verma, Rohit
author_facet Sharma, Richa
Sharma, Sunil Dutt
Agarwal, Priyanka
Avasthi, Devesh Kumar
Verma, Rohit
author_sort Sharma, Richa
collection PubMed
description AIM: The response of ionization chamber changes when used at beam quality Q which is different from beam quality Q(o) (usually (60)Co) that was used at the time of its calibration. Hence, one needs to apply beam quality correction factor (k(Q, Qo)) during dosimetric measurements. However, k(Q, Qo) data are unavailable for novel ion chambers in the literature. Moreover, most of such data do not differentiate between filtered (flat) and unfiltered (unflat) beams. In addition, literature-based data do not differentiate among different pieces of the ion chambers of the same make and model. Hence, the purpose of our study was to determine the ion chamber-specific experimental values of k(Q, Qo) and to evaluate their impact in dosimetry. MATERIALS AND METHODS: In this work, the value of k(Q, Qo) were measured for six ionization chambers of three different types in 6, 10, and 15 MV filtered (with flattening filter [WFF]) as well as 6 and 10 MV unfiltered (flattening filter free [FFF]) photon beams. The measured values of k(Q, Qo) were compared with Monte Carlo-calculated values available in the literature. The uncertainties in measurement of k(Q, Qo) values were also evaluated. RESULTS: For 6 MV FFF beam, the measured value of k(Q, Qo) was found to be consistently lower than 6 MV WFF beam for all Sun Nuclear Corporation ion chambers, while it was higher as per the theoretical data. The inter-chamber variation in k(Q, Qo) values was observed for the same model of the ion chambers. The maximum difference between absolute dose values on using the theoretical and experimental k(Q, Qo) values was up to 3.23%. CONCLUSION: The measured absolute dose values by the ion chamber of a given make and model were found different due to the use of its theoretical and experimental k(Q, Qo) values. Furthermore, the variation in response of different pieces of ion chambers of the same make and model cannot be accounted for theoretically, and hence, the use of theoretical k(Q, Qo) data may introduce an inherent error in the estimation of absorbed dose to water. This necessitates the use of measured value of k(Q, Qo) for each ionization chamber.
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spelling pubmed-95429912022-10-08 Evaluating the Impact of Ionization Chamber-Specific Beam Quality Correction Factor in Dosimetry of Filtered and Unfiltered Photon Beams Sharma, Richa Sharma, Sunil Dutt Agarwal, Priyanka Avasthi, Devesh Kumar Verma, Rohit J Med Phys Original Article AIM: The response of ionization chamber changes when used at beam quality Q which is different from beam quality Q(o) (usually (60)Co) that was used at the time of its calibration. Hence, one needs to apply beam quality correction factor (k(Q, Qo)) during dosimetric measurements. However, k(Q, Qo) data are unavailable for novel ion chambers in the literature. Moreover, most of such data do not differentiate between filtered (flat) and unfiltered (unflat) beams. In addition, literature-based data do not differentiate among different pieces of the ion chambers of the same make and model. Hence, the purpose of our study was to determine the ion chamber-specific experimental values of k(Q, Qo) and to evaluate their impact in dosimetry. MATERIALS AND METHODS: In this work, the value of k(Q, Qo) were measured for six ionization chambers of three different types in 6, 10, and 15 MV filtered (with flattening filter [WFF]) as well as 6 and 10 MV unfiltered (flattening filter free [FFF]) photon beams. The measured values of k(Q, Qo) were compared with Monte Carlo-calculated values available in the literature. The uncertainties in measurement of k(Q, Qo) values were also evaluated. RESULTS: For 6 MV FFF beam, the measured value of k(Q, Qo) was found to be consistently lower than 6 MV WFF beam for all Sun Nuclear Corporation ion chambers, while it was higher as per the theoretical data. The inter-chamber variation in k(Q, Qo) values was observed for the same model of the ion chambers. The maximum difference between absolute dose values on using the theoretical and experimental k(Q, Qo) values was up to 3.23%. CONCLUSION: The measured absolute dose values by the ion chamber of a given make and model were found different due to the use of its theoretical and experimental k(Q, Qo) values. Furthermore, the variation in response of different pieces of ion chambers of the same make and model cannot be accounted for theoretically, and hence, the use of theoretical k(Q, Qo) data may introduce an inherent error in the estimation of absorbed dose to water. This necessitates the use of measured value of k(Q, Qo) for each ionization chamber. Wolters Kluwer - Medknow 2022 2022-08-05 /pmc/articles/PMC9542991/ /pubmed/36212211 http://dx.doi.org/10.4103/jmp.jmp_101_21 Text en Copyright: © 2022 Journal of Medical Physics https://creativecommons.org/licenses/by-nc-sa/4.0/This is an open access journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms.
spellingShingle Original Article
Sharma, Richa
Sharma, Sunil Dutt
Agarwal, Priyanka
Avasthi, Devesh Kumar
Verma, Rohit
Evaluating the Impact of Ionization Chamber-Specific Beam Quality Correction Factor in Dosimetry of Filtered and Unfiltered Photon Beams
title Evaluating the Impact of Ionization Chamber-Specific Beam Quality Correction Factor in Dosimetry of Filtered and Unfiltered Photon Beams
title_full Evaluating the Impact of Ionization Chamber-Specific Beam Quality Correction Factor in Dosimetry of Filtered and Unfiltered Photon Beams
title_fullStr Evaluating the Impact of Ionization Chamber-Specific Beam Quality Correction Factor in Dosimetry of Filtered and Unfiltered Photon Beams
title_full_unstemmed Evaluating the Impact of Ionization Chamber-Specific Beam Quality Correction Factor in Dosimetry of Filtered and Unfiltered Photon Beams
title_short Evaluating the Impact of Ionization Chamber-Specific Beam Quality Correction Factor in Dosimetry of Filtered and Unfiltered Photon Beams
title_sort evaluating the impact of ionization chamber-specific beam quality correction factor in dosimetry of filtered and unfiltered photon beams
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9542991/
https://www.ncbi.nlm.nih.gov/pubmed/36212211
http://dx.doi.org/10.4103/jmp.jmp_101_21
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