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Evaluation of Surface Dose and Commissioning of Compensator-Based Total Body Irradiation

PURPOSE: The aim of the current study is to commission compensator-based total body irradiation (TBI) and to compare surface dose using percentage depth dose (PDD) while varying the distance between beam spoiler and phantom surface. MATERIALS AND METHODS: TBI commissioning was performed on Elekta Sy...

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Autores principales: Pandu, Bharath, Khanna, D., Mohandass, P., Ninan, Hima, Elavarasan, Rajadurai, Jacob, Saro, Sunny, Goutham
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer - Medknow 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9542993/
https://www.ncbi.nlm.nih.gov/pubmed/36212207
http://dx.doi.org/10.4103/jmp.jmp_137_21
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author Pandu, Bharath
Khanna, D.
Mohandass, P.
Ninan, Hima
Elavarasan, Rajadurai
Jacob, Saro
Sunny, Goutham
author_facet Pandu, Bharath
Khanna, D.
Mohandass, P.
Ninan, Hima
Elavarasan, Rajadurai
Jacob, Saro
Sunny, Goutham
author_sort Pandu, Bharath
collection PubMed
description PURPOSE: The aim of the current study is to commission compensator-based total body irradiation (TBI) and to compare surface dose using percentage depth dose (PDD) while varying the distance between beam spoiler and phantom surface. MATERIALS AND METHODS: TBI commissioning was performed on Elekta Synergy® Platform linear accelerator for bilateral extended source to surface distance treatment technique. The PDD was measured by varying the distance (10 cm, 20 cm, 30 cm, and 40 cm) between the beam spoiler and the phantom surface. Beam profile and half-value layer (HVL) measurement were carried out using the FC65 ion-chamber. Quality assurance (QA) was performed using an in-house rice-flour phantom (RFP). In-vivo diodes (IVD) were placed on the RFP at various regions to measure the delivered dose, and it was compared to the calculated dose. RESULTS: An increase in Dmax and surface dose was observed when beam spoiler was moved away from the phantom surface. The flatness and symmetry of the beam profile were calculated. The HVL of Perspex and aluminum is 17 cm and 8 cm, respectively. The calculated dose of each region was compared to the measured dose on the RFP with IVD, and the findings showed that the variation was <4.7% for both Perspex and Aluminum compensators. CONCLUSION: The commissioning of the compensator-based TBI technique was performed and its QA measurements were carried out. The Mayneord factor corrected PDD and measured PDD values were compared. The results are well within the clinical tolerance limit. This study concludes that 10 cm −20 cm is the optimal distance from the beam spoiler to phantom surface to achieve prescribed dose to the skin.
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spelling pubmed-95429932022-10-08 Evaluation of Surface Dose and Commissioning of Compensator-Based Total Body Irradiation Pandu, Bharath Khanna, D. Mohandass, P. Ninan, Hima Elavarasan, Rajadurai Jacob, Saro Sunny, Goutham J Med Phys Original Article PURPOSE: The aim of the current study is to commission compensator-based total body irradiation (TBI) and to compare surface dose using percentage depth dose (PDD) while varying the distance between beam spoiler and phantom surface. MATERIALS AND METHODS: TBI commissioning was performed on Elekta Synergy® Platform linear accelerator for bilateral extended source to surface distance treatment technique. The PDD was measured by varying the distance (10 cm, 20 cm, 30 cm, and 40 cm) between the beam spoiler and the phantom surface. Beam profile and half-value layer (HVL) measurement were carried out using the FC65 ion-chamber. Quality assurance (QA) was performed using an in-house rice-flour phantom (RFP). In-vivo diodes (IVD) were placed on the RFP at various regions to measure the delivered dose, and it was compared to the calculated dose. RESULTS: An increase in Dmax and surface dose was observed when beam spoiler was moved away from the phantom surface. The flatness and symmetry of the beam profile were calculated. The HVL of Perspex and aluminum is 17 cm and 8 cm, respectively. The calculated dose of each region was compared to the measured dose on the RFP with IVD, and the findings showed that the variation was <4.7% for both Perspex and Aluminum compensators. CONCLUSION: The commissioning of the compensator-based TBI technique was performed and its QA measurements were carried out. The Mayneord factor corrected PDD and measured PDD values were compared. The results are well within the clinical tolerance limit. This study concludes that 10 cm −20 cm is the optimal distance from the beam spoiler to phantom surface to achieve prescribed dose to the skin. Wolters Kluwer - Medknow 2022 2022-08-05 /pmc/articles/PMC9542993/ /pubmed/36212207 http://dx.doi.org/10.4103/jmp.jmp_137_21 Text en Copyright: © 2022 Journal of Medical Physics https://creativecommons.org/licenses/by-nc-sa/4.0/This is an open access journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms.
spellingShingle Original Article
Pandu, Bharath
Khanna, D.
Mohandass, P.
Ninan, Hima
Elavarasan, Rajadurai
Jacob, Saro
Sunny, Goutham
Evaluation of Surface Dose and Commissioning of Compensator-Based Total Body Irradiation
title Evaluation of Surface Dose and Commissioning of Compensator-Based Total Body Irradiation
title_full Evaluation of Surface Dose and Commissioning of Compensator-Based Total Body Irradiation
title_fullStr Evaluation of Surface Dose and Commissioning of Compensator-Based Total Body Irradiation
title_full_unstemmed Evaluation of Surface Dose and Commissioning of Compensator-Based Total Body Irradiation
title_short Evaluation of Surface Dose and Commissioning of Compensator-Based Total Body Irradiation
title_sort evaluation of surface dose and commissioning of compensator-based total body irradiation
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9542993/
https://www.ncbi.nlm.nih.gov/pubmed/36212207
http://dx.doi.org/10.4103/jmp.jmp_137_21
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