Orbital Exenteration and Brachytherapy for the Treatment of Pediatric, Fusion-positive, Recurrent Rhabdomyosarcoma

A 20-month-old boy presented with biopsy-proven recurrent alveolar rhabdomyosarcoma without metastasis. He was previously treated with multiagent chemotherapy and external beam irradiation showing a complete response. Upon relapse, he was treated with chemotherapy, orbital exenteration, and brachyth...

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Detalles Bibliográficos
Autores principales: Lopez, Joseph, Qin, Nancy, Woods, Robbie, Golden, Marjorie, Spatz, Harrison, Shah, Jatin, Wexler, Leonard H., Randazzo, Joseph, Wolden, Suzanne L., Abramson, David H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2022
Materias:
Craniofacial/Pediatric
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9543036/
https://www.ncbi.nlm.nih.gov/pubmed/36225848
http://dx.doi.org/10.1097/GOX.0000000000004581
Descripción
Sumario:A 20-month-old boy presented with biopsy-proven recurrent alveolar rhabdomyosarcoma without metastasis. He was previously treated with multiagent chemotherapy and external beam irradiation showing a complete response. Upon relapse, he was treated with chemotherapy, orbital exenteration, and brachytherapy. Customized, intraoperative brachytherapy has potential to limit the sequelae associated with radiation adjuvant therapy.

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