Orbital Exenteration and Brachytherapy for the Treatment of Pediatric, Fusion-positive, Recurrent Rhabdomyosarcoma

A 20-month-old boy presented with biopsy-proven recurrent alveolar rhabdomyosarcoma without metastasis. He was previously treated with multiagent chemotherapy and external beam irradiation showing a complete response. Upon relapse, he was treated with chemotherapy, orbital exenteration, and brachyth...

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Autores principales: Lopez, Joseph, Qin, Nancy, Woods, Robbie, Golden, Marjorie, Spatz, Harrison, Shah, Jatin, Wexler, Leonard H., Randazzo, Joseph, Wolden, Suzanne L., Abramson, David H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2022
Materias:
Craniofacial/Pediatric
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9543036/
https://www.ncbi.nlm.nih.gov/pubmed/36225848
http://dx.doi.org/10.1097/GOX.0000000000004581
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author Lopez, Joseph
Qin, Nancy
Woods, Robbie
Golden, Marjorie
Spatz, Harrison
Shah, Jatin
Wexler, Leonard H.
Randazzo, Joseph
Wolden, Suzanne L.
Abramson, David H.
author_facet Lopez, Joseph
Qin, Nancy
Woods, Robbie
Golden, Marjorie
Spatz, Harrison
Shah, Jatin
Wexler, Leonard H.
Randazzo, Joseph
Wolden, Suzanne L.
Abramson, David H.
author_sort Lopez, Joseph
collection PubMed
description A 20-month-old boy presented with biopsy-proven recurrent alveolar rhabdomyosarcoma without metastasis. He was previously treated with multiagent chemotherapy and external beam irradiation showing a complete response. Upon relapse, he was treated with chemotherapy, orbital exenteration, and brachytherapy. Customized, intraoperative brachytherapy has potential to limit the sequelae associated with radiation adjuvant therapy.
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spelling pubmed-95430362022-10-11 Orbital Exenteration and Brachytherapy for the Treatment of Pediatric, Fusion-positive, Recurrent Rhabdomyosarcoma Lopez, Joseph Qin, Nancy Woods, Robbie Golden, Marjorie Spatz, Harrison Shah, Jatin Wexler, Leonard H. Randazzo, Joseph Wolden, Suzanne L. Abramson, David H. Plast Reconstr Surg Glob Open Craniofacial/Pediatric A 20-month-old boy presented with biopsy-proven recurrent alveolar rhabdomyosarcoma without metastasis. He was previously treated with multiagent chemotherapy and external beam irradiation showing a complete response. Upon relapse, he was treated with chemotherapy, orbital exenteration, and brachytherapy. Customized, intraoperative brachytherapy has potential to limit the sequelae associated with radiation adjuvant therapy. Lippincott Williams & Wilkins 2022-10-07 /pmc/articles/PMC9543036/ /pubmed/36225848 http://dx.doi.org/10.1097/GOX.0000000000004581 Text en Copyright © 2022 The Authors. Published by Wolters Kluwer Health, Inc. on behalf of The American Society of Plastic Surgeons. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution-Non Commercial-No Derivatives License 4.0 (CCBY-NC-ND) (https://creativecommons.org/licenses/by-nc-nd/4.0/) , where it is permissible to download and share the work provided it is properly cited. The work cannot be changed in any way or used commercially without permission from the journal.
spellingShingle Craniofacial/Pediatric
Lopez, Joseph
Qin, Nancy
Woods, Robbie
Golden, Marjorie
Spatz, Harrison
Shah, Jatin
Wexler, Leonard H.
Randazzo, Joseph
Wolden, Suzanne L.
Abramson, David H.
Orbital Exenteration and Brachytherapy for the Treatment of Pediatric, Fusion-positive, Recurrent Rhabdomyosarcoma
title Orbital Exenteration and Brachytherapy for the Treatment of Pediatric, Fusion-positive, Recurrent Rhabdomyosarcoma
title_full Orbital Exenteration and Brachytherapy for the Treatment of Pediatric, Fusion-positive, Recurrent Rhabdomyosarcoma
title_fullStr Orbital Exenteration and Brachytherapy for the Treatment of Pediatric, Fusion-positive, Recurrent Rhabdomyosarcoma
title_full_unstemmed Orbital Exenteration and Brachytherapy for the Treatment of Pediatric, Fusion-positive, Recurrent Rhabdomyosarcoma
title_short Orbital Exenteration and Brachytherapy for the Treatment of Pediatric, Fusion-positive, Recurrent Rhabdomyosarcoma
title_sort orbital exenteration and brachytherapy for the treatment of pediatric, fusion-positive, recurrent rhabdomyosarcoma
topic Craniofacial/Pediatric
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9543036/
https://www.ncbi.nlm.nih.gov/pubmed/36225848
http://dx.doi.org/10.1097/GOX.0000000000004581
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